Fatty acid breath test values in the malabsorption range in cancer patients

Journal Article · Fri Jan 01 00:00:00 EST 1982 · Nutr. Cancer; (United States)

OSTI ID:6430502

Delaney, W E; Stuart, R K; Ettinger, D S

Fatty acid absorption breath tests (FABT) were found to be abnormal in most subjects in a group of cancer patients selected to exclude common causes of abnormal lipid absorption, including chemotherapy and radiation therapy. The breath tests were abnormal in both quality (delayed peak in 9 of 10 patients) and quantity (reduced maximum peak in 5 of 10 patients) of fatty acid absorption. Retrospective separation of patients into 2 groups (normal or low maximum peak height FABT), either at a common time after the start of the test or at each individual's maximum peak height FABT regardless of time, was significant at 0.005 and 0.001, respectively. The low maximum peak heights were in the range of the malabsorption syndrome. Further studies of pancreatic function and fat malabsorption are warranted before the abnormal results can be ascribed to altered intermediary metabolism or peripheral utilization of lipids.

• Research Organization: Oncology Unit, Lankenau Hospital, Philadelphia, PA
• OSTI ID: 6430502
• Journal Information: Nutr. Cancer; (United States), Vol. 3:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
CARBON 14 COMPOUNDS
DIAGNOSTIC USES
LIPIDS
METABOLISM
NEOPLASMS
PATHOLOGY
ABSORPTION
BREATH
CARBOXYLIC ACIDS
PATIENTS
QUALITATIVE CHEMICAL ANALYSIS
CHEMICAL ANALYSIS
DISEASES
LABELLED COMPOUNDS
ORGANIC ACIDS
ORGANIC COMPOUNDS
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550901 - Pathology- Tracer Techniques
550201 - Biochemistry- Tracer Techniques
551001 - Physiological Systems- Tracer Techniques