Focus: DNA probes
Journal Article
·
· Anal. Chem.; (United States)
OSTI ID:6415389
Progress in the development of DNA probes for the identification and quantitation of specific genetic sequences in biological samples is reviewed. Current research efforts in the development of DNA probes for the diagnosis of a wide variety of bacterial, viral, and other infectious diseases, such as herpes simplex and cytomegalovirus, and inherited genetic diseases such as cystic fibrosis and sickle cell anemia are discussed. Progress in development of DNA probe assays for cancer diagnosis, detection of Salmonella food poisoning, tissue typing (detection of histocompatibility antigens), mutagen screening, and animal diseases, among other applications is included.
- OSTI ID:
- 6415389
- Journal Information:
- Anal. Chem.; (United States), Vol. 58:13
- Country of Publication:
- United States
- Language:
- English
Similar Records
Allele-specific enzymatic amplification of. beta. -globin genomic DNA for diagnosis of sickle cell anemia
With current gene markers, presymptomatic diagnosis of heritable disease is still a family affair
Evidence for a founder effect for the IVS4 +4 A{r_arrow}T mutation in the Fanconi anemia gene FACC in a Jewish population
Journal Article
·
Sat Apr 01 00:00:00 EST 1989
· Proceedings of the National Academy of Sciences of the United States of America; (USA)
·
OSTI ID:6415389
+1 more
With current gene markers, presymptomatic diagnosis of heritable disease is still a family affair
Journal Article
·
Fri Sep 04 00:00:00 EDT 1987
· JAMA, J. Am. Med. Assoc.; (United States)
·
OSTI ID:6415389
Evidence for a founder effect for the IVS4 +4 A{r_arrow}T mutation in the Fanconi anemia gene FACC in a Jewish population
Journal Article
·
Thu Sep 01 00:00:00 EDT 1994
· American Journal of Human Genetics
·
OSTI ID:6415389
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL MATERIALS
GENETIC MAPPING
DIAGNOSTIC USES
DIAGNOSIS
HEREDITARY DISEASES
HYBRIDIZATION
IMMUNITY
INFECTIOUS DISEASES
MUTAGEN SCREENING
NEOPLASMS
RESEARCH PROGRAMS
REVIEWS
DISEASES
DOCUMENT TYPES
MAPPING
MATERIALS
SCREENING
USES
550400* - Genetics
550600 - Medicine
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL MATERIALS
GENETIC MAPPING
DIAGNOSTIC USES
DIAGNOSIS
HEREDITARY DISEASES
HYBRIDIZATION
IMMUNITY
INFECTIOUS DISEASES
MUTAGEN SCREENING
NEOPLASMS
RESEARCH PROGRAMS
REVIEWS
DISEASES
DOCUMENT TYPES
MAPPING
MATERIALS
SCREENING
USES
550400* - Genetics
550600 - Medicine