Malignant fibrous histiocytoma of the breast. A case report and review of the literature

Journal Article · Wed Aug 01 00:00:00 EDT 1984 · Cancer (Philadelphia); (United States)

DOI:https://doi.org/10.1002/1097-0142(19840801)54:3<558::AID-CNCR2820540329>3.0.CO;2-6· OSTI ID:6221641

Langham, Jr, M R; Mills, A S; DeMay, R M; O'Dowd, G J; Grathwohl, M A; Horsley, J S

The clinicopathologic features of a malignant fibrous histiocytoma arising in a female breast are presented. Seven cases have been previously reported. These may be divided into three subgroups based on history and pathologic findings. Three of the seven occurred in women without a history of other tumors or previous irradiation. One appeared with a cystosarcoma phyllodes, and three arose following radiation for carcinoma of the breast. The patient in this study had received no radiation. Treatment has been based on surgical resection; the roles of chemotherapy and radiation are uncertain. Although resection alone in the first subgroup has lead to no reported mortality, the small number of cases and the relatively short follow-up does not allow a meaningful assessment of the prognosis in this disease.

• Research Organization: Medical Coll. of Virginia, Richmond
• OSTI ID: 6221641
• Journal Information: Cancer (Philadelphia); (United States), Vol. 54:3
• Country of Publication: United States
• Language: English

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