Relationship of blood cadmium level to hypertension and plasma norepinephrine level: a Romanian study (41159)
The associations of blood cadmium levels with hypertension and plasma norepinephrine concentrations were determined in normotensive and hypertensive nonsmokers and smokers. Statistical analysis showed that after adjustment for age alone, the estimated mean values of blood cadmium and plasma norepinephrine in nonsmokers were significantly lower than in smokers. However, after adjustment for age and blood cadmium, the estimated mean values for plasma norepinephrine were not significantly different between nonsmokers and smokers or normotensives and hypertensives. In contrast the estimated mean value for blood cadmium as a function of blood pressure and smoking habit was still significant after adjustment for age and plasma norepinephrine. We suggest that smoking and blood pressure affect the level of blood cadmium, and through this change in blood cadmium the level of plasma norepinephrine is affected.
- Research Organization:
- Oak Ridge National Lab., TN
- DOE Contract Number:
- W-7405-ENG-26
- OSTI ID:
- 6187335
- Journal Information:
- Proc. Soc. Exp. Biol. Med.; (United States), Vol. 167:2
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
BLOOD CHEMISTRY
CORRELATIONS
BLOOD PRESSURE
PATHOLOGICAL CHANGES
CADMIUM COMPOUNDS
BIOLOGICAL EFFECTS
HYPERTENSION
TOBACCO SMOKES
AGE GROUPS
BLOOD PLASMA
CATIONS
HUMAN POPULATIONS
NORADRENALINE
ADRENAL HORMONES
AEROSOLS
AUTONOMIC NERVOUS SYSTEM AGENTS
BIOLOGICAL MATERIALS
BLOOD
BODY FLUIDS
CARDIOTONICS
CARDIOVASCULAR AGENTS
CARDIOVASCULAR DISEASES
CHARGED PARTICLES
COLLOIDS
DISEASES
DISPERSIONS
DRUGS
HORMONES
IONS
MATERIALS
NEUROREGULATORS
POPULATIONS
RESIDUES
SMOKES
SOLS
STEROID HORMONES
SYMPATHOMIMETICS
SYMPTOMS
VASCULAR DISEASES
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)