Mesothelial papillary proliferation of the pleura associated with radiation therapy: Does it have a role in the pathogenesis of mesothelioma

Journal Article · Wed Mar 01 00:00:00 EST 1989 · Mt. Sinai J. Med.; (United States)

OSTI ID:5815759

Jagirdar, J; Frydman, C; Sakurai, H; Dumitrescu, O

Diffuse papillary proliferation of mesothelial cells in the pleura mimicking metastatic carcinoma was seen four weeks following radiation therapy for a Pancoast tumor. Such papillary proliferations are not observed incidentally and are envisioned to occur during asbestos-induced carcinogenesis. We postulate that similar papillary lesions may serve as a link in the pathogenesis of radiation-induced mesotheliomas.

• OSTI ID: 5815759
• Journal Information: Mt. Sinai J. Med.; (United States), Vol. 56:2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
NEOPLASMS
RADIOINDUCTION
PLEURA
BIOLOGICAL RADIATION EFFECTS
RADIOTHERAPY
SIDE EFFECTS
CARCINOMAS
CELL PROLIFERATION
EPITHELIUM
LUNGS
MAN
METASTASES
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BODY
DISEASES
MAMMALS
MEDICINE
MEMBRANES
NUCLEAR MEDICINE
ORGANS
PRIMATES
RADIATION EFFECTS
RADIOLOGY
RESPIRATORY SYSTEM
SEROUS MEMBRANES
THERAPY
TISSUES
VERTEBRATES
560151* - Radiation Effects on Animals- Man