Renal gallium accumulation in the absence of renal pathology in patients with severe hepatocellular disease

Journal Article · Sun May 01 00:00:00 EDT 1983 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198305000-00003· OSTI ID:5745215

Alazraki, N; Sterkel, B; Taylor, A Jr

Visualization of Ga-67 citrate in the kidneys at 48 hours and 72 hours post injection is usually interpreted as evidence of renal pathology. In reviewing approximately 200 consecutive patients referred for gallium scans, 40 patients who also underwent liver/spleen Tc-99m sulfur colloid (SC) studies within one month of the gallium study were identified. Fourteen of these patients showed advanced hepatocellular dysfunction on the Tc-99m SC liver/spleen images. Of these 14 patients, nine had persistent renal accumulation of gallium at 48 or 72 hours. Five of these nine patients had no evidence of primary renal disease by clinical or postmortem examination and subsequent clinical information indicated that two additional patients probably had no significant renal pathology. Therefore, bilateral symmetrically increased renal uptake of gallium in patients with advanced hepatocellular disease should not necessarily be interpreted as evidence of renal pathology.

• Research Organization: Nuclear Medicine Service, VA Medical Center, San Diego, California
• OSTI ID: 5745215
• Journal Information: Clin. Nucl. Med.; (United States), Vol. 8:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
GALLIUM 67
DIAGNOSTIC USES
TISSUE DISTRIBUTION
LIVER CIRRHOSIS
DIAGNOSTIC TECHNIQUES
NEPHRITIS
TECHNETIUM 99
AUTOPSY
IMAGES
ISOMERIC NUCLEI
KIDNEYS
MALES
MAN
PATIENTS
RADIOCOLLOIDS
SPLEEN
SULFUR
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COLLOIDS
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM DISEASES
DISEASES
DISPERSIONS
DISTRIBUTION
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
GALLIUM ISOTOPES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
NONMETALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PRIMATES
RADIOISOTOPES
TECHNETIUM ISOTOPES
UROGENITAL SYSTEM DISEASES
USES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics