Renal functional recovery of the hydronephrotic kidney predicted before relief of the obstruction
Employing technetium labeled dimercaptosuccinic acid, we predicted the inulin and p-aminohippuric acid (PAH) clearances after recovery of an obstructed kidney before relief of the obstruction. Sixteen rabbits had one renal unit obstructed for varying period of time. The animals were scanned immediately before relief of the obstruction. After 4 to 6 months recovery, inulin and PAH clearances were measured in all animals. The scans were mathematically analyzed, and accurately predicted the inulin and PAH clearances obtained after complete recovery (P less than 0.001 and P less than 0.001, respectively). Six rabbits were scanned at the time of the clearance measurements. By a different mathematical analysis, inulin and PAH clearance measured concurrently correlated with the scan (P less than 0.001 and P less than 0.01 respectively).
- OSTI ID:
- 5638835
- Journal Information:
- Invest. Urol.; (United States), Vol. 18:8
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
KIDNEYS
SCINTISCANNING
TECHNETIUM 99
ISOTOPE APPLICATIONS
BIOLOGICAL RECOVERY
CLEARANCE
DYNAMIC FUNCTION STUDIES
FORECASTING
HIPPURIC ACID
INULIN
ISOMERIC NUCLEI
NEPHRITIS
RABBITS
SUCCINIC ACID
AMINO ACIDS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOHYDRATES
CARBOXYLIC ACIDS
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DICARBOXYLIC ACIDS
DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
POLYSACCHARIDES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RECOVERY
SACCHARIDES
TECHNETIUM ISOTOPES
UROGENITAL SYSTEM DISEASES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550200 - Biochemistry
551001 - Physiological Systems- Tracer Techniques