skip to main content

Title: Congenital vocal cord paralysis with possible autosomal recessive inheritance: Case report and review of the literature

We describe an infant with congenital vocal cord paralysis born to consanguineous parents. While autosomal dominant and X-linked inheritance have been previously reported in this condition, we conclude that the degree of parental consanguinity in this case strongly suggests autosomal recessive inheritance. Although we cannot exclude X-linked inheritance, evidence from animal studies demonstrates autosomal recessive inheritance and provides a possible molecular basis for congenital vocal cord paralysis. 14 refs., 1 fig.
Authors:
; ;  [1]
  1. Long Island Campus for the Albert Einstein College of Medicine, New Hyde Park, NY (United States)
Publication Date:
OSTI Identifier:
539405
Resource Type:
Journal Article
Resource Relation:
Journal Name: American Journal of Medical Genetics; Journal Volume: 64; Journal Issue: 3; Other Information: PBD: 23 Aug 1996
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; SENSE ORGANS DISEASES; GENETICS; INFANTS; CONGENITAL DISEASES; HEREDITARY DISEASES; PHENOTYPE; GENES; GENETIC MAPPING; GENE MUTATIONS; GENE REGULATION; HUMAN CHROMOSOMES; SENSE ORGANS; RECESSIVE MUTATIONS