Carbogen breathing during radiation therapy. The radiation therapy oncology group study
Journal Article
·
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
- Univ. of Rochester Cancer Center, NY
The Radiation Therapy Oncology Group (RTOG) Study, in which 254 patients were analyzed, adjunctive carbogen breathing in irradiation of carcinomas of the oral cavity, oropharynx, nasopharynx, hypopharynx, and larynx failed to bring aboout a gain in survival at any of these sites. In only two of the five regional subgroups did results show any improvement with respect to patients in the Carbogen group as compared to those in the Air group, i.e., the larynx and hypopharynx subgroups. Since both of these subgroups contained relatively small numbers of patients (42 larynx, 39 hypopharynx), it was not possible to declare these improvements as definitely due to carbogen breathing. In the case of the larynx subgroup, improvement might have been due to the slightly unequal distribution with respect to T-stage; in either subgroup, the possibility that apparent improvement was due to nothing more than random variation could not be ruled out. In the subgroups with larger numbers of patients, i.e., the oral cavity and oropharynx groups, there was no demonstrated improvement accompanying carbogen breathing.
- OSTI ID:
- 5366264
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 5:11-12; ISSN IOBPD
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
BODY AREAS
BREATH
CARCINOMAS
CRYOGENIC FLUIDS
DATA
DATA FORMS
DIGESTIVE SYSTEM
DISEASES
EDEMA
ELECTROMAGNETIC RADIATION
ELEMENTS
FIBROSIS
FISTULAE
FLUIDS
HEAD
INFORMATION
IONIZING RADIATIONS
MEDICINE
NECK
NECROSIS
NEOPLASMS
NONMETALS
NUCLEAR MEDICINE
ORAL CAVITY
OXYGEN
PATHOLOGICAL CHANGES
PATIENTS
RADIATIONS
RADIOLOGY
RADIOSENSITIVITY EFFECTS
RADIOTHERAPY
SIDE EFFECTS
SYMPTOMS
TABLES
THERAPY
X RADIATION
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
BODY AREAS
BREATH
CARCINOMAS
CRYOGENIC FLUIDS
DATA
DATA FORMS
DIGESTIVE SYSTEM
DISEASES
EDEMA
ELECTROMAGNETIC RADIATION
ELEMENTS
FIBROSIS
FISTULAE
FLUIDS
HEAD
INFORMATION
IONIZING RADIATIONS
MEDICINE
NECK
NECROSIS
NEOPLASMS
NONMETALS
NUCLEAR MEDICINE
ORAL CAVITY
OXYGEN
PATHOLOGICAL CHANGES
PATIENTS
RADIATIONS
RADIOLOGY
RADIOSENSITIVITY EFFECTS
RADIOTHERAPY
SIDE EFFECTS
SYMPTOMS
TABLES
THERAPY
X RADIATION