Quantitative studies in radiopharmaceutical science. Progress report, April 1-August 31, 1986

Technical Report · Mon Sep 01 00:00:00 EDT 1986

OSTI ID:5331137

Cooper, M

This report covers progress made during the first reporting period since the redirection of the project. In radiochemistry, achievements in fluorine-18 tracer studies including purification and reaction kinetics of 2-fluorodeoxyglucose and production of 6-fluoroDOPA. Radiopharmaceuticals have been prepared and tested for studies on CNS dopaminergic systems. By use of dynamic positron emission tomography the cerebral transport and metabolism of glucose continues to be studied. 6 figs.

• Research Organization: Chicago Univ., IL (USA)
• DOE Contract Number: FG02-86ER60438
• OSTI ID: 5331137
• Report Number(s): DOE/ER/60438-1; ON: DE87000216
• Resource Relation: Other Information: Portions of this document are illegible in microfiche products
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
59 BASIC BIOLOGICAL SCIENCES
BROMINE 75
CHEMICAL PREPARATION
BROMINE 76
DOPA
LABELLING
DOPAMINE
BIOLOGICAL FUNCTIONS
FLUORINE 18
NEUROREGULATORS
ANATOMY
CARBON 11
CEREBELLUM
CEREBRUM
DIABETES MELLITUS
FLUORINATED ALIPHATIC HYDROCARBONS
FLUORODEOXYGLUCOSE
MACACUS
MICE
OXYGEN 15
POSITRON COMPUTED TOMOGRAPHY
RADIOCHEMISTRY
SYMPATHOLYTICS
AMINES
AMINO ACIDS
ANIMALS
ANTIMETABOLITES
AROMATICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
BRAIN
BROMINE ISOTOPES
CARBON ISOTOPES
CARBOXYLIC ACIDS
CARDIOTONICS
CARDIOVASCULAR AGENTS
CENTRAL NERVOUS SYSTEM
CHEMISTRY
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
ENDOCRINE DISEASES
EVEN-ODD NUCLEI
FLUORINE ISOTOPES
FUNCTIONS
HALOGENATED ALIPHATIC HYDROCARBONS
HOURS LIVING RADIOISOTOPES
HYDROXY ACIDS
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIGHT NUCLEI
MAMMALS
METABOLIC DISEASES
MINUTES LIVING RADIOISOTOPES
MONKEYS
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC FLUORINE COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANS
OXYGEN ISOTOPES
PHENOLS
POLYPHENOLS
PRIMATES
RADIOISOTOPES
RODENTS
SYMPATHOMIMETICS
SYNTHESIS
TOMOGRAPHY
VERTEBRATES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
400702 - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials
550801 - Morphology- Tracer Techniques