Candidiasis of the liver and spleen in childhood
Four children with acute leukemia and surgically documented candidiasis of the liver and/or spleen were examined with a combination of diagnostic imaging modalities including /sup 99/mTc-sulfur colloid and /sup 67/Ga-citrate scintigraphy, gray-scale ultrasound, and body computed tomography (CT). Abnormalities were detected in every individual examined. /sup 99/mTc-sulfur colloid scintigraphy revealed cold areas in the liver or spleen. With /sup 67/Ga scintigraphy, these areas were cold in some individuals and hot in others. Gray-scale ultrasound demonstrated hypoechoic lesions with central areas of increased echogenicity in hepatic involvement, and hypoechoic replacement of the spleen in splenic involvement. CT in one patient revealed low-density areas without contrast enhancement within the hepatic parenchyma and unsuspected renal involvement.
- Research Organization:
- Division of Nuclear Radiology and Diagnostic Ultrasound, Childrens Hospital of Los Angeles, CA
- OSTI ID:
- 5284716
- Journal Information:
- Radiology; (United States), Vol. 142:2
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
ABSCESSES
DIAGNOSIS
CHILDREN
SCINTISCANNING
GALLIUM 67
DIAGNOSTIC USES
LIVER
TECHNETIUM 99
CITRIC ACID ESTERS
COMPUTERIZED TOMOGRAPHY
ISOMERIC NUCLEI
PATIENTS
RADIOCOLLOIDS
SPLEEN
ULTRASONOGRAPHY
AGE GROUPS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACID ESTERS
COLLOIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISPERSIONS
ELECTRON CAPTURE RADIOISOTOPES
ESTERS
GALLIUM ISOTOPES
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
TOMOGRAPHY
USES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550901 - Pathology- Tracer Techniques