skip to main content

Title: Thyroid function following neck irraidation for malignant lymphoma

Thyroid function tests for T/sub 3/ resin (T/sub 3/-r), serum thyroxine (T/sub 4/), and serum thyroid stimulating hormone (TSH) were measured in 70 consecutive patients who had previously undergone lymphangiography and neck irradiation for malignant lymphoma. All were in remission and clinically euthyroid. The abnormalities found were: 23 (33%) patients hypothyroid by TSH, 14 (20%) with subnormal T/sub 4/, and 21 (30%) with subnormal T/sub 3/-r values. None of the patients were biochemically hyperthyroid. The prevalence and magnitude of abnormalities were highest during the third year after irradiation, thereafter decreasing with time.
Authors:
; ;
Publication Date:
OSTI Identifier:
5246591
Resource Type:
Journal Article
Resource Relation:
Journal Name: Radiology; (United States); Journal Volume: 134:1
Research Org:
Univ. Hospital, Ann Arbor, MI
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; HYPOTHYROIDISM; RADIOINDUCTION; RADIOTHERAPY; SIDE EFFECTS; THYROID; DELAYED RADIATION EFFECTS; CESIUM 137; COBALT 60; GAMMA RADIATION; LYMPHOMAS; NECK; PARTIAL BODY IRRADIATION; PATIENTS; THYROXINE; TIME DEPENDENCE; TRIIODOTHYRONINE; TSH; ALKALI METAL ISOTOPES; AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; BODY AREAS; CARBOXYLIC ACIDS; CESIUM ISOTOPES; COBALT ISOTOPES; DISEASES; ELECTROMAGNETIC RADIATION; ENDOCRINE DISEASES; ENDOCRINE GLANDS; EXTERNAL IRRADIATION; GLANDS; HORMONES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANS; PEPTIDE HORMONES; PITUITARY HORMONES; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RADIOLOGY; THERAPY; THYROID HORMONES; YEARS LIVING RADIOISOTOPES 560151* -- Radiation Effects on Animals-- Man; 550603 -- Medicine-- External Radiation in Therapy-- (1980-)