Radiation induced carcinoma of the larynx

Journal Article · Mon Jul 01 00:00:00 EDT 1985 · Surg. Gynecol. Obstet.; (United States)

OSTI ID:5243218

Amendola, B E; Amendola, M A; McClatchey, K D

A squamous cell carcinoma presented in a 20 year old female nonsmoker three years after receiving a high dosage of radiation therapy to the base of the skull, face and entire neuroaxis and intense combination chemotherapy for a parameningeal rhabdomyosarcoma of the paranasal sinuses is reported. The larynx received a dose of about 3,500 rads over an eight week period. This dosage in conjunction with the associated intense chemotherapy regimen given to the patient may explain the appearance of a radiation induced tumor in an unusually short latent period. This certainly represents a risk in young patients in whom an aggressive combined approach is taken and the physician should be aware of.

• Research Organization: Univ. of Michigan Medical Center, Ann Arbor
• OSTI ID: 5243218
• Journal Information: Surg. Gynecol. Obstet.; (United States), Vol. 1
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
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CARCINOMAS
RADIOINDUCTION
RADIOTHERAPY
CHEMOTHERAPY
SIDE EFFECTS
LARYNX
RADIATION DOSES
BIOLOGICAL RADIATION EFFECTS
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MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
RADIATION EFFECTS
RADIOLOGY
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