Historical cohort study of mortality among chemical researchers

Journal Article · Sat Mar 01 00:00:00 EST 1986 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1986.9937419· OSTI ID:5229396

Maher, K V; Defonso, L R

This historical cohort study examined mortality among 1,510 white male researchers employed from 1950-1959 who handled chemicals. During 1950-1979, 95 deaths were observed, significantly less than the 173.2 predicted by general population rates (SMR = 55). This was due to deficits in overall cancer deaths (SMR = 66), particularly respiratory cancer (SMR = 28), and reduced mortality from circulatory diseases and accidents. Those who had worked directly with chemicals for more than 5 yr and those who had the most hazardous exposures experienced similar low mortality for all causes, all cancers, and respiratory cancer. Although deaths due to digestive cancer were elevated among those with 1-5 yr of work experience, there was no excess among those working more than 5 yr as would be expected from occupational exposure.

• Research Organization: Rohm and Haas Co., Bristol, PA
• OSTI ID: 5229396
• Journal Information: Arch. Environ. Health; (United States), Vol. 2
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CHEMICAL INDUSTRY
PROFESSIONAL PERSONNEL
MORTALITY
CARCINOMAS
CARDIOVASCULAR DISEASES
DIGESTIVE SYSTEM DISEASES
EPIDEMIOLOGY
NEOPLASMS
OCCUPATIONAL DISEASES
PENNSYLVANIA
POLYMERS
RESPIRATORY SYSTEM DISEASES
DISEASES
FEDERAL REGION III
INDUSTRY
NORTH AMERICA
PERSONNEL
USA
560306* - Chemicals Metabolism & Toxicology- Man- (-1987)