Analysis of serial radionuclide bone images in osteosarcoma and breast carcinoma

Journal Article · Tue Apr 01 00:00:00 EST 1980 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.135.1.6928697· OSTI ID:5179993

McNeil, B J; Hanley, J

The authors first describe and illustrate didactically the use of the Kaplan-Meier actuarial technique for serial diagnostic studies. They then present an analysis of previously published data on the results of serial radionuclide bone images in patients with osteosarcoma or breast carcinoma, using this technique. The data indicate that patients with osteosarcoma show an almost linear increase in the occurrence of bone metastates between 5 and 29 months after diagnosis; the rate is approximately 1% per month. Patients with breast cancer, on the other hand, show a biphasic rate of development, averaging only 0.5% per month during the first year after diagnosis but increasing rapidly to approximately 2% per month after 15 months.

• Research Organization: Harvard Medical School, Cambridge, MA
• OSTI ID: 5179993
• Journal Information: Radiology; (United States), Vol. 135:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARCINOMAS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DATA ANALYSIS
METASTASES
OSTEOSARCOMAS
SKELETON
SCINTISCANNING
MAMMARY GLANDS
PATIENTS
PROBABILITY
TABLES
TIME DEPENDENCE
BODY
COUNTING TECHNIQUES
DATA FORMS
DISEASES
GLANDS
NEOPLASMS
ORGANS
RADIOISOTOPE SCANNING
SARCOMAS
SKELETAL DISEASES
550601* - Medicine- Unsealed Radionuclides in Diagnostics