Nonsyndromic cleft lip with or without cleft palate: New BCL3 information
Journal Article
·
· American Journal of Human Genetics
OSTI ID:478524
- Univ. of Texas Medical School, Houston, TX (United States)
- Univ. of Pennsylvania School of Medicine, Philadelphia, PA (United States)
We did not previously provide LOD scores for linkage assuming heterogeneity, as suggested by Ott for the linkage analysis of cleft lip with or without cleft palate (CL/P) and BCL3, ApoC2, and D19S178 in the paper by Stein et al. The results from analysis using the HOMOG program, allowing for heterogeneity under the reduced penetrance model, gave a maximum LOD score of 1.85 for ApoC2, 0.41 for BCL3, 0.03 for D19S178, and 1.72 for multipoint analysis in the interval. For the affecteds-only model, the values are 1.96 for ApoC2, 0.41 for BCL3, 0.01 for D19S178, and 1.44 for the multipoint analysis. 8 refs.
- OSTI ID:
- 478524
- Journal Information:
- American Journal of Human Genetics, Vol. 59, Issue 3; Other Information: PBD: Sep 1996
- Country of Publication:
- United States
- Language:
- English
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