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Title: Location of the handedness gene on the X and Y chromosomes

Journal Article · · American Journal of Medical Genetics
;  [1];  [2];  [3]
  1. Univ. of Auckland (New Zealand)
  2. Univ. College London (United Kingdom)
  3. Warneford Hospital, Oxford (United Kingdom)

Accumulated data from five handedness surveys show that concordance for sex is slightly but reliably higher among siblings of the same handedness than among those of opposite handedness. This is consistent with Crow`s theory that the genetic locus for handedness is in an X-Y homologous region of the sex chromosomes. The small size of the effect is predicted from genetic models in which there is a substantial random component underlying phenotypic left handedness. The findings are relevant to the putative role of cerebral asymmetry in the aetiology of psychosis. 15 refs., 3 tabs.

OSTI ID:
437196
Journal Information:
American Journal of Medical Genetics, Vol. 67, Issue 1; Other Information: PBD: 16 Feb 1996
Country of Publication:
United States
Language:
English