Cadmium concentrations in the brains of Alzheimer cases
- Univ. of Surrey, Guildford (United Kingdom)
There is ongoing research in relating the concentration of elements in the brain with Alzheimer`s disease. The presence of particular elements, such as aluminum and vanadium, has been considered as a possible environmental factor, creating significant interest and controversy in the field. We have been analyzing brain tissue from the MRC Alzheimer`s Disease Brain Bank, Institute of Psychiatry, from a number of cortical regions of the brain, namely, the frontal, occipital, parietal, and temporal lobes, as well as from the left and right hemispheres of the same brain whenever possible. The techniques employed have been proton-induced X-ray emission (PIXE) analysis, proton-induced gamma-ray emission (PIGE) analysis, Rutherford backscattering (RBS), and instrumental neutron activation analysis. Neutron irradiations were carried out at the Imperial College Consort II reactor, whereas for PIXE, PIGE, and RBS, the University of Surrey Accelerator Laboratories were used employing a Van de Graaff accelerator. In this paper, we present the cadmium results from the frontal lobe of Alzheimer cases and controls determined by PIXE analysis.
- OSTI ID:
- 436776
- Report Number(s):
- CONF-9606116-; ISSN 0003-018X; TRN: 96:005275-0005
- Journal Information:
- Transactions of the American Nuclear Society, Vol. 74; Conference: Annual meeting of the American Nuclear Society (ANS), Reno, NV (United States), 16-20 Jun 1996; Other Information: PBD: 1996
- Country of Publication:
- United States
- Language:
- English
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