Carbon-14 Kinetic Isotope Effects. III. ^1,2 The Hydrolysis of 2-Chloro-2-methylpropane-2-C ¹⁴

Journal Article · Fri Aug 01 04:00:00 UTC 1958 · Journal of the American Chemical Society

DOI:https://doi.org/10.1021/ja01549a047· OSTI ID:4307767

Bender, Myron L.; Buist, Gabriel J.

pared from sodlum acetate-1-C¹⁴. The kinetics of hydrolysis of the unlabeled compound in 60% dioxane--40% water were determined. The kinetic isotope effect in the hydrolysis of 2-chloro-2-methylpropane-2-C¹⁴ was determined by radioassay of the hydrolysis product, 2-methyl-2 derivative) at various fractions of reaction. The kinetic isotope effect (k₁₂k₁₄ was found to be 1.027 plus or minus 0.015. This kinetic isotope effect in an Sn1 (two-center reaction) is less than the kinetic isotope effects found in a number of Sn2 (three-center reactions) involving methyl these kinetic isotope effects probably reflect differences in the leaving groups as well as differences in the mechanisms of the processes.

• Research Organization: Illinois Inst. of Tech., Chicago
• Sponsoring Organization: USDOE
• NSA Number: NSA-12-016279
• OSTI ID: 4307767
• Journal Information: Journal of the American Chemical Society, Journal Name: Journal of the American Chemical Society Journal Issue: 16 Vol. 80; ISSN 0002-7863
• Publisher: American Chemical Society (ACS)
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
CARBON 14
DECOMPOSITION
DIOXANE
HYDROLYSIS
IODIDES
ISOTOPE EFFECTS
MECHANICS
METHYL RADICALS
ORGANIC CHLORINE COMPOUNDS
PROPANE
RADIATION CHEMISTRY
REACTION KINETICS
SOLUTIONS
SOLVENTS
WATER