Time-resolved photon emission from layered turbid media

Journal Article · Thu Feb 01 00:00:00 EST 1996 · Applied Optics

DOI:https://doi.org/10.1364/AO.35.000719· OSTI ID:367240

Hielscher, A H ^[1]; Liu, H; Chance, B ^[2]; Tittel, F K ^[1]; Jacques, S L ^[3]

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1. Department of Electrical and Computer Engineering, Rice University, 6100 South Main, Houston, Texas 77251-1892 (United States)
2. Department of Biochemistry and Biophysics, University of Pennsylvania, D501 Richards Building, Philadelphia, Pennsylvania 19104-6089 (United States)
3. Laser Biology Research Laboratory, Box 17, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030 (United States)

We present numerical and experimental results of time-resolved emission profiles from various layered turbid media. Numerical solutions determined by time-resolved Monte Carlo simulations are compared with measurements on layered-tissue phantoms made from gelatin. In particular, we show that in certain cases the effects of the upper layers can be eliminated. As a practical example, these results are used to analyze {ital in} {ital vivo} measurements on the human head. This demonstrates the influence of skin, skull, and meninges on the determination of the blood oxygenation in the brain. {copyright} {ital 1996 Optical Society of America.}

• Sponsoring Organization: USDOE
• OSTI ID: 367240
• Journal Information: Applied Optics, Vol. 35, Issue 4; Other Information: PBD: Feb 1996
• Country of Publication: United States
• Language: English

Related Subjects

66 PHYSICS
ANIMAL TISSUES
PHOTON TRANSPORT
EMISSION SPECTRA
TURBIDITY
MONTE CARLO METHOD
COMPUTERIZED SIMULATION
LAYERS
ABSORPTIVITY
NEAR INFRARED RADIATION