CFTR gene variant IVS8-5T in disseminated bronchiectasis

Journal Article · Mon Apr 01 00:00:00 EST 1996 · American Journal of Human Genetics

OSTI ID:285072

Pignatti, P F; Bombieri, C; Benetazzo, M; Casartelli, A ^[1]

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1. Univ. of Verona (Italy); and others

Obstructive pulmonary disease includes asthma, chronic obstructive pulmonary disease (COPD; i.e., pulmonary emphysema and chronic bronchitis), bronchiectasis, and cystic fibrosis (CF). It represents a leading cause of death in developed countries. Both familial clustering of non-CF obstructive pulmonary disease and familial aggregation of impaired lung function have been described. This suggests that genetic factors contribute to non-CF obstructive pulmonary disease, even if it is difficult to determine the relative contribution of environmental factors. 11 refs., 1 tab.

• OSTI ID: 285072
• Journal Information: American Journal of Human Genetics, Vol. 58, Issue 4; Other Information: PBD: Apr 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
GENES
GENE MUTATIONS
RESPIRATORY SYSTEM DISEASES
PATIENTS
HEREDITARY DISEASES
GENOTYPE
NUCLEOTIDES
POLYMERASE CHAIN REACTION