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Title: Microfocus x-ray imaging of traceable pointlike {sup 22}Na sources for quality control

Journal Article · · Medical Physics
DOI:https://doi.org/10.1118/1.4730293· OSTI ID:22100647
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  1. Allied Health Sciences, Kitasato University Kitasato 1-15-1, Minami-ku, Sagamihara-shi, Kanagawa 252-0373 (Japan)

Purpose: The purpose of this study is to propose a microfocus x-ray imaging technique for observing the internal structure of small radioactive sources and evaluating geometrical errors quantitatively, and to apply this technique to traceable pointlike {sup 22}Na sources, which were designed for positron emission tomography calibration, for the purpose of quality control of the pointlike sources. Methods: A microfocus x-ray imaging system with a focus size of 0.001 mm was used to obtain projection x-ray images and x-ray CT images of five pointlike source samples, which were manufactured during 2009-2012. The obtained projection and tomographic images were used to observe the internal structure and evaluate geometrical errors quantitatively. Monte Carlo simulation was used to evaluate the effect of possible geometrical errors on the intensity and uniformity of 0.511 MeV annihilation photon pairs emitted from the sources. Results: Geometrical errors were evaluated with sufficient precision using projection x-ray images. CT images were used for observing the internal structure intuitively. As a result, four of the five examined samples were within the tolerance to maintain the total uncertainty below {+-}0.5%, given the source radioactivity; however, one sample was found to be defective. Conclusions: This quality control procedure is crucial and offers an important basis for using the pointlike {sup 22}Na source as a basic calibration tool. The microfocus x-ray imaging approach is a promising technique for visual and quantitative evaluation of the internal geometry of small radioactive sources.

OSTI ID:
22100647
Journal Information:
Medical Physics, Vol. 39, Issue 7; Other Information: (c) 2012 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-2405
Country of Publication:
United States
Language:
English