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Title: Improving quality assurance for assembled COMS eye plaques using a pinhole gamma camera

Journal Article · · Medical Physics
DOI:https://doi.org/10.1118/1.2975152· OSTI ID:22095209
; ; ;  [1]
  1. Radiation Medicine Program, Princess Margaret Hospital, 610 University Avenue, Toronto, Ontario M5G 2M9 (Canada)

A quality assurance system has been designed to verify the location and strength of seeds loaded in a brachytherapy eye plaque. This system consists of (1) a pinhole camera in conjunction with a Lumisys ACR-2000i computed radiography (CR) unit to image the location and measure the relative strength of the seeds with autoradiography, and (2) a source strength jig with a survey meter to estimate the total activity of the seeds in the plaque. Five holders of different sizes were made for fixation of the COMS (Collaborative Ocular Melanoma Study) plaques (12, 14, 16, 18, and 20 mm) in the camera. The plaque-to-pinhole distance (d{sub pp}) has been optimized to be 30 mm to give approximately uniform intensity on the CR image for uniformly loaded COMS plaques. The pinhole-to-detector distance (d{sub pd}) can be kept at either 30 mm for 1:1 scale, or at larger distances for higher magnification. For a 1:1 scaling and pinhole diameter of 0.345 mm, useful images are obtained with time-activity product (mCi sec) ranging from 5 to 250 mCi sec. Within this range, the pinhole system is able to differentiate seed activities of >10%. The resulting pinhole autoradiograph is able to (1) confirm the correct number of seeds loaded in the plaque, (2) verify the proper sitting of the seeds in the silastic carrier and the plaque, (3) verify the relative activity distribution of the seeds loaded in the plaque, and (4) potentially evaluate the integrity of the seed. The source strength measurement system is able to measure the total strength of seeds in the plaque ranging from 10 to 80 mCi with an uncertainty of 5%.

OSTI ID:
22095209
Journal Information:
Medical Physics, Vol. 35, Issue 10; Other Information: (c) 2008 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-2405
Country of Publication:
United States
Language:
English

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