Calcium Oxalate Stones Are Frequently Found Attached to Randall's Plaque
- James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, 4940 Eastern Ave / Room A 345, Baltimore, Maryland 21224 (United States)
- Departments of Anatomy and Cell Biology, Indiana University School of Medicine, 635 Barnhill Dr /MS 5035, Indianapolis, Indiana, 46202 (United States)
- Methodist Hospital Institute for Kidney Stone Disease, 1801 N. Senate Blvd, Suite 220, Indianapolis, Indiana, 46202 (United States)
The exact mechanisms of the crystallization processes that occur during the formation of calcium oxalate calculi are controversial. Over six decades ago, Alexander Randall reported on a series of cadaveric renal units in which he observed calcium salt deposits on the tips of the renal papilla. Randall hypothesized that these deposits, eponymously termed Randall's plaque, would be the ideal site for stone formation, and indeed in a number of specimens he noted small stones attached to the papillae. With the recent advent of digital endoscopic imaging and micro computerized tomography (CT) technology, it is now possible to inspect the renal papilla of living, human stone formers and to study the attached stone with greater scrutiny.
- OSTI ID:
- 21056959
- Journal Information:
- AIP Conference Proceedings, Vol. 900, Issue 1; Conference: 1. Annual international urolithiasis research symposium, Indianapolis, IN (United States), 2-3 Nov 2006; Other Information: DOI: 10.1063/1.2723557; (c) 2007 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
- Country of Publication:
- United States
- Language:
- English
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