XXXII. An account of the success of the bark of the willow in the cure of agues. In a letter to the Right Honourable George Earl of Macclesfield, President of R. S. from the Rev. Mr. Edward Stone, of Chipping-Norton in Oxfordshire
|
journal
|
January 1763 |
Untersuchungen über das Salicin und die daraus entstehenden Producte
|
journal
|
January 1839 |
Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs
|
journal
|
June 1971 |
Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets
|
journal
|
June 1971 |
Indomethacin and Aspirin abolish Prostaglandin Release from the Spleen
|
journal
|
June 1971 |
Inhibition of platelet prostaglandin synthetase by oral aspirin.
|
journal
|
February 1978 |
COX-2 inhibitors
|
journal
|
January 1999 |
Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation
|
journal
|
April 2008 |
Interrelationships between Prostacyclin and Thromboxane A 2
|
book
|
January 1980 |
Withdrawal of COX-2 selective inhibitors rofecoxib and valdecoxib: impact on NSAID and gastroprotective drug prescribing and utilization
|
journal
|
June 2007 |
Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target
|
journal
|
September 2007 |
Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
|
journal
|
June 1999 |
Identification and development of mPGES-1 inhibitors: where we are at?
|
journal
|
November 2011 |
Microsomal Prostaglandin E Synthase Type 2 (mPGES2) Is a Glutathione-dependent Heme Protein, and Dithiothreitol Dissociates the Bound Heme to Produce Active Prostaglandin E2 Synthase in Vitro
|
journal
|
April 2013 |
Inhibitors of Microsomal Prostaglandin E 2 Synthase-1 Enzyme as Emerging Anti-Inflammatory Candidates: INHIBITORS OF mPGES-1 ENZYME
|
journal
|
January 2014 |
MF63 [2-(6-Chloro-1 H -phenanthro[9,10- d ]imidazol-2-yl)-isophthalonitrile], a Selective Microsomal Prostaglandin E Synthase-1 Inhibitor, Relieves Pyresis and Pain in Preclinical Models of Inflammation
|
journal
|
June 2008 |
Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886
|
journal
|
July 2005 |
Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor
|
journal
|
May 2010 |
Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation
|
journal
|
February 2013 |
Pharmacokinetic–pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors
|
journal
|
April 2005 |
Inhibition of prostacyclin and thromboxane A2 generation by low-dose aspirin at the site of plug formation in man in vivo.
|
journal
|
May 1987 |
The Biochemical Selectivity of Novel COX-2 Inhibitors in Whole Blood Assays of COX-isozyme Activity
|
journal
|
January 2002 |
Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics
|
journal
|
May 2015 |
Time-dependent CYP inhibition
|
journal
|
February 2007 |
Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death
|
journal
|
January 2005 |
Characterization of a new mPGES-1 inhibitor in rat models of inflammation
|
journal
|
April 2013 |
Supersaturating Drug Delivery Systems: The Answer to Solubility-Limited Oral Bioavailability?
|
journal
|
August 2009 |
Quantitative Analysis of the Effect of Supersaturation on in Vivo Drug Absorption
|
journal
|
October 2010 |
Effect of gastric pH on the pharmacokinetics of a bcs class II compound in dogs: Utilization of an artificial stomach and duodenum dissolution model and gastroplus,™ simulations to predict absorption
|
journal
|
November 2011 |
Synthesis and Antifungal Activity of New Azole Derivatives Containing an N-Acylmorpholine Ring
|
journal
|
September 1995 |
Transformations of N-Heteroarylformamidines. A Novel Synthesis of Imidazo[2,1-b]thiazole and Imidazo[2,1-b][1,3,4]thiadiazole Derivatives
|
journal
|
January 1986 |
Esterification of Carboxylic Acids and Etherification of Phenols with Amide Acetals
|
journal
|
June 2008 |
The influence of drug-like concepts on decision-making in medicinal chemistry
|
journal
|
November 2007 |
Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry: IMIDAZOLE-BASED MEDICINAL CHEMISTRY
|
journal
|
June 2013 |
The impact of aromatic ring count on compound developability: further insights by examining carbo- and hetero-aromatic and -aliphatic ring types
|
journal
|
February 2011 |
Ueber die N-Methylolverbindungen der Säureamide [Erste Abhandlung.]
|
journal
|
January 1905 |