Laser machined plastic laminates. Towards portable diagnostic devices for use in low resource environments

Journal Article · Tue Jul 14 00:00:00 EDT 2015 · Electroanalysis

DOI:https://doi.org/10.1002/elan.201500359· OSTI ID:1237655

Harper, Jason C. ^[1]; Carson, Bryan D. ^[1]; Bachand, George D. ^[1]; Arndt, William D. ^[1]; Finley, Melissa R. ^[1]; Brinker, C. Jeffrey ^[1]; Edwards, Thayne L. ^[1]

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1. Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Despite significant progress in development of bioanalytical devices cost, complexity, access to reagents and lack of infrastructure have prevented use of these technologies in resource-limited regions. To provide a sustainable tool in the global effort to combat infectious diseases the diagnostic device must be low cost, simple to operate and read, robust, and have sensitivity and specificity comparable to laboratory analysis. Thus, in this mini-review we describe recent work using laser machined plastic laminates to produce diagnostic devices that are capable of a wide variety of bioanalytical measurements and show great promise towards future use in low-resource environments.

• Research Organization: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
• Sponsoring Organization: USDOE National Nuclear Security Administration (NNSA)
• Grant/Contract Number: AC04-94AL85000
• OSTI ID: 1237655
• Report Number(s): SAND-2015-4078J; 584060
• Journal Information: Electroanalysis, Vol. 27, Issue 11; ISSN 1040-0397
• Publisher: Wiley
• Country of Publication: United States
• Language: English

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low-resource environment bioanalytics
laser ablated plastic laminates
electrode arrays
DNA detection
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