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Title: An open source platform for multi-scale spatially distributed simulations of microbial ecosystems

Technical Report ·
DOI:https://doi.org/10.2172/1228383· OSTI ID:1228383
 [1]
  1. Boston Univ., MA (United States)

The goal of this project was to develop a tool for facilitating simulation, validation and discovery of multiscale dynamical processes in microbial ecosystems. This led to the development of an open-source software platform for Computation Of Microbial Ecosystems in Time and Space (COMETS). COMETS performs spatially distributed time-dependent flux balance based simulations of microbial metabolism. Our plan involved building the software platform itself, calibrating and testing it through comparison with experimental data, and integrating simulations and experiments to address important open questions on the evolution and dynamics of cross-feeding interactions between microbial species.

Research Organization:
Boston Univ., MA (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER)
DOE Contract Number:
SC0004962
OSTI ID:
1228383
Report Number(s):
DE-SC0004962
Country of Publication:
United States
Language:
English

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