skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

Journal Article · · PLoS Neglect Trop. D.

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
National Institutes of Health (NIH)
OSTI ID:
1224487
Journal Information:
PLoS Neglect Trop. D., Vol. 9, Issue 10; ISSN 1935-2727
Country of Publication:
United States
Language:
ENGLISH

References (19)

Isolation of a female-specific, highly repeated Schistosoma mansoni DNA probe and its use in an assay of cercarial sex journal October 1989
Enzymatic basis for the lack of oxamniquine activity in Schistosoma haematobium infections journal August 1997
Evidence for the mode of antischistosomal action of hycanthone journal July 1985
High-Performance liquid chromatographic resolution of oxamniquine enantiomers: Application to in vitro metabolism studies journal January 1990
The Protein Data Bank journal January 2000
Studies with the schistosomicide oxamniquine (uk-4271) II. Activity in primates journal January 1973
Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites journal November 2013
Epidemiological and control aspects of schistosomiasis in Brazilian endemic areas journal August 2004
The schistosome enzyme that activates oxamniquine has the characteristics of a sulfotransferase journal October 2006
Resolution of the enantiomers of oxamniquine by capillary electrophoresis and high-performance liquid chromatography with cyclodextrins and heparin as chiral selectors journal May 1995
In vitro metabolism studies on oxamniquine and related compounds by chiral liquid chromatography journal January 1989
XDS journal January 2010
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
Features and development of Coot journal March 2010
Experimental chemotherapy ofSchistosoma mansoni with praziquantel and oxamniquine: differential effect of single or combined formulations of drugs on various strains and on both sexes of the parasite journal January 1992
PARP1 exhibits enhanced association and catalytic efficiency with γH2A.X-nucleosome journal December 2019
Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation journal February 2021
PHENIX: a comprehensive Python-based system for macromolecular structure solution. text January 2010
IUPAC Commission on Nomenclature of Organic Chemistry book January 1976

Cited By (1)

Schistosomiasis journal August 2018