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Title: Fat to muscle ratio measurements with dual energy x-ray absorbtiometry

Journal Article · · Nuclear Instruments and Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment
 [1];  [2];  [3];  [4];  [5];  [6];  [7];  [7]
  1. Shenzhen College of International Education; GuangDong (China)
  2. Univ. at Buffalo, Buffalo, NY (United States)
  3. Carnegie Mellon Univ., Pittsburgh, PA (United States)
  4. Columbia Univ., New York, NY (United States)
  5. Dartmouth College, Hanover, NH (United States)
  6. Stony Brook Univ., Stony Brook, NY (United States)
  7. Brookhaven National Lab. (BNL), Upton, NY (United States)
+ Show Author Affiliations

Accurate measurement of the fat-to-muscle ratio in animal model is important for obesity research. In addition, an efficient way to measure the fat to muscle ratio in animal model using dual-energy absorptiometry is presented in this paper. A radioactive source exciting x-ray fluorescence from a target material is used to provide the two x-ray energies needed. The x-rays, after transmitting through the sample, are measured with an energy-sensitive Ge detector. Phantoms and specimens were measured. The results showed that the method was sensitive to the fat to muscle ratios with good linearity. A standard deviation of a few percent in the fat to muscle ratio could be observed with the x-ray dose of 0.001 mGy.

Research Organization:
Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
Grant/Contract Number:
SC00112704; AC02-98CH10886; 05–057
OSTI ID:
1193200
Alternate ID(s):
OSTI ID: 1247382
Report Number(s):
BNL-107905-2015-JA; R&D Project: LS001
Journal Information:
Nuclear Instruments and Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 788, Issue C; ISSN 0168-9002
Publisher:
ElsevierCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 2 works
Citation information provided by
Web of Science

References (6)

Quantification of adiposity in small rodents using micro-CT journal January 2010
Clinical Use of Bone Densitometry: Scientific Review journal October 2002
Synchrotron radiation coronary angiography with a dual-beam, dual-detector imaging system
  • Rubenstein, E.; Giacomini, J. C.; Gordon, H. J.
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 291, Issue 1-2 https://doi.org/10.1016/0168-9002(90)90037-7
journal May 1990
First human transvenous coronary angiography at the European Synchrotron Radiation Facility journal August 2000
Dynamic intravenous coronary angiography using 2D monochromatic synchrotron radiation. journal January 1999
A bent Laue crystal monochromator for monochromatic radiography with an area beam
  • Zhong, Z.; Chapman, D.; Thomlinson, W.
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 399, Issue 2-3 https://doi.org/10.1016/S0168-9002(97)00969-8
journal November 1997

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Related Subjects

36 MATERIALS SCIENCE
dual energy x-ray
absorptiometry
obesity research
fat-to-muscle ratio