Reversible centriole depletion with an inhibitor of Polo-like kinase 4

Wong, Yao Liang; Anzola, John V.; Davis, Robert L.; Yoon, Michelle; Motamedi, Amir; Kroll, Ashley; Seo, Chanmee P.; Hsia, Judy E.; Kim, Sun K.; Mitchell, Jennifer W.; Mitchell, Brian J.; Desai, Arshad; Gahman, Timothy C.; Shiau, Andrew K.; Oegema, Karen

doi:10.1126/science.aaa5111

Title: Reversible centriole depletion with an inhibitor of Polo-like kinase 4

Journal Article · Thu Jun 04 00:00:00 EDT 2015 · Science

DOI:https://doi.org/10.1126/science.aaa5111· OSTI ID:1184861

Wong, Yao Liang; Anzola, John V.; Davis, Robert L.; Yoon, Michelle; Motamedi, Amir; Kroll, Ashley; Seo, Chanmee P.; Hsia, Judy E.; Kim, Sun K.; Mitchell, Jennifer W.; Mitchell, Brian J.; Desai, Arshad; Gahman, Timothy C.; Shiau, Andrew K.; Oegema, Karen ^[1]

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Research Organization:: Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: NIHOTHER

OSTI ID:: 1184861

Journal Information:: Science, Vol. 348, Issue 06, 2015

Country of Publication:: United States

Language:: ENGLISH

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Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Joseph, Nimesh; Al-Jassar, Caezar; Johnson, Christopher M. Elsevier BV https://doi.org/10.17863/cam.26288	journalarticle	January 2018
Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse. Coelho, Paula A.; Bury, Leah; Shahbazi, Marta N. The Royal Society https://doi.org/10.17863/cam.38792	journalarticle	January 2015
The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis Potapova, Tamara; Gorbsky, Gary Biology, Vol. 6, Issue 4 https://doi.org/10.3390/biology6010012	journal	February 2017
De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly Wang, Won-Jing; Acehan, Devrim; Kao, Chien-Han eLife, Vol. 4 https://doi.org/10.7554/elife.10586	journal	November 2015

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