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Title: Neutron Technologies for Bioenergy Research

Journal Article · · Industrial Biotechnology

Neutron scattering is a powerful technique that can be used to probe the structures and dynamics of complex systems. It can provide a fundamental understanding of the processes involved in the production of biofuels from lignocellulosic biomass. A variety of neutron scattering technologies are available to elucidate both the organization and deconstruction of this complex composite material and the associations and morphology of the component polymers and the enzymes acting on them, across multiple length scales ranging from Angstroms to micrometers and time scales from microseconds to picoseconds. Unlike most other experimental techniques, neutron scattering is uniquely sensitive to hydrogen (and its isotope deuterium), an atom abundantly present throughout biomass and a key effector in many biological, chemical, and industrial processes for producing biofuels. Sensitivity to hydrogen, the ability to replace hydrogen with deuterium to alter scattering levels, the fact that neutrons cause little or no direct radiation damage, and the ability of neutrons to exchange thermal energies with materials, provide neutron scattering technologies with unique capabilities for bioenergy research. Further, neutrons are highly penetrating, making it possible to employ sample environments that are not suitable for other techniques. The true power of neutron scattering is realized when it is combined with computer simulation and modeling and contrast variation techniques enabled through selective deuterium labeling.

Research Organization:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). High Flux Isotope Reactor (HFIR); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Spallation Neutron Source (SNS); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Center for Structural Molecular Biology (CSMB)
Sponsoring Organization:
USDOE Laboratory Directed Research and Development (LDRD) Program
DOE Contract Number:
DE-AC05-00OR22725
OSTI ID:
1050360
Journal Information:
Industrial Biotechnology, Vol. 8, Issue 4; ISSN 1550-9087
Country of Publication:
United States
Language:
English