Why do we get Alzheimer's disease?
Abstract
Neurodegenerative diseases and Alzheimer's disease (AD) in particular, are among the major health concerns of the elderly in industrialized societies. The cause of AD is unknown and no disease-modifying treatments are available. The disease is characterized clinically by a progressive dementia and pathologically by the accumulation of protein aggregates in the brain and a profound loss of nerve cells. It has also become clear recently that local immune responses are activated in the AD brain and may have a role in the disease. Our laboratory uses genetic mouse models to understand the disease process and to identify potential therapeutic targets.
- Authors:
- Publication Date:
- Research Org.:
- SLAC (SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States))
- Sponsoring Org.:
- USDOE Office of Science (SC)
- OSTI Identifier:
- 987523
- DOE Contract Number:
- AC02-76SF00515
- Resource Type:
- Multimedia
- Resource Relation:
- Conference: SLAC Public Lecture Series, SLAC National Accelerator Laboratory, Menlo Park, California, presented on October 02, 2006
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 43 PARTICLE ACCELERATORS
Citation Formats
Wyss-Coray, Tony. Why do we get Alzheimer's disease?. United States: N. p., 2006.
Web.
Wyss-Coray, Tony. Why do we get Alzheimer's disease?. United States.
Wyss-Coray, Tony. Mon .
"Why do we get Alzheimer's disease?". United States. https://www.osti.gov/servlets/purl/987523.
@article{osti_987523,
title = {Why do we get Alzheimer's disease?},
author = {Wyss-Coray, Tony},
abstractNote = {Neurodegenerative diseases and Alzheimer's disease (AD) in particular, are among the major health concerns of the elderly in industrialized societies. The cause of AD is unknown and no disease-modifying treatments are available. The disease is characterized clinically by a progressive dementia and pathologically by the accumulation of protein aggregates in the brain and a profound loss of nerve cells. It has also become clear recently that local immune responses are activated in the AD brain and may have a role in the disease. Our laboratory uses genetic mouse models to understand the disease process and to identify potential therapeutic targets.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Oct 02 00:00:00 EDT 2006},
month = {Mon Oct 02 00:00:00 EDT 2006}
}