The linac coherent light source single particle imaging road map

Journal Article · Tue Apr 21 04:00:00 UTC 2015 · Structural Dynamics

DOI: https://doi.org/10.1063/1.4918726 · OSTI ID:2565459

Aquila, A.; Barty, A.; Bostedt, C.; Boutet, S.; Carini, G.; dePonte, D.; Drell, P.; Doniach, S.; Downing, K. H.; Earnest, T.; Elmlund, H.; Elser, V.; Gühr, M.; Hajdu, J.; Hastings, J.; Hau-Riege, S. P.; Huang, Z.; Lattman, E. E.; Maia, F. R. N. C.; Marchesini, S. ; Ourmazd, A.; Pellegrini, C.; Santra, R.; Schlichting, I.; Schroer, C.; Spence, J. C. H.; Vartanyants, I. A.; Wakatsuki, S.; Weis, W. I.; Williams, G. J.

Intense femtosecond x-ray pulses from free-electron laser sources allow the imaging of individual particles in a single shot. Early experiments at the Linac Coherent Light Source (LCLS) have led to rapid progress in the field and, so far, coherent diffractive images have been recorded from biological specimens, aerosols, and quantum systems with a few-tens-of-nanometers resolution. In March 2014, LCLS held a workshop to discuss the scientific and technical challenges for reaching the ultimate goal of atomic resolution with single-shot coherent diffractive imaging. This paper summarizes the workshop findings and presents the roadmap toward reaching atomic resolution, 3D imaging at free-electron laser sources.

• Sponsoring Organization: USDOE
• Grant/Contract Number: AC02-76SF00515; AC52-07NA27344; SC0002164
• OSTI ID: 2565459
• Journal Information: Structural Dynamics, Journal Name: Structural Dynamics Journal Issue: 4 Vol. 2; ISSN 2329-7778
• Publisher: American Institute of PhysicsCopyright Statement
• Country of Publication: United States
• Language: English