Stability of Polyethylene Glycol-Coated Copper Nanoparticles and Their Optical Properties

Okyere, Deborah; Manso, Ryan H.; Tong, Xiao; Chen, Jingyi

doi:10.3390/coatings12060776

Title: Stability of Polyethylene Glycol-Coated Copper Nanoparticles and Their Optical Properties

Full Record
Other Related Research

Abstract

Oxidation is a corrosion reaction where the corroded metal forms an oxide. Prevention of oxidation at the nanoscale is critically important to retain the physicochemical properties of metal nanoparticles. In this work, we studied the stability of polyethylene glycol (PEG) coated copper nanoparticles (PEGylated CuNPs) against oxidation. The freshly-prepared PEGylated CuNPs mainly consist of metallic Cu which are quite stable in air although their surfaces are typically covered with a few monolayers of cuprous oxide. However, they are quickly oxidized in water due to the presence of protons that facilitate oxidation of the cuprous oxide to cupric oxide. PEG with carboxylic acid terminus could slightly delay the oxidation process compared to that with thiol terminus. It was found that a solvent with reducing power such as ethanol could greatly enhance the stability of PEGylated CuNPs by preventing further oxidation of the cuprous oxide to cupric oxide and thus retain the optical properties of CuNPs. The reducing environment also assists the galvanic replacement of these PEGylated CuNPs to form hollow nanoshells; however, they consist of ultra-small particle assemblies due to the co-reduction of gold precursor during the replacement reaction. As a result, these nanoshells do not exhibit strong optical properties inmore »« less

Authors:

Okyere, Deborah; Manso, Ryan H.; Tong, Xiao;

Publication Date:: Sat Jun 04 00:00:00 EDT 2022

Research Org.:: Brookhaven National Lab. (BNL), Upton, NY (United States)

Sponsoring Org.:: USDOE Office of Science (SC), Basic Energy Sciences (BES); National Science Foundation (NSF)

OSTI Identifier:: 1871264

Alternate Identifier(s):: OSTI ID: 1876829

Report Number(s):: BNL-223137-2022-JAAM
Journal ID: ISSN 2079-6412; COATED; PII: coatings12060776

Grant/Contract Number:: SC0012704; 1826642

Resource Type:: Published Article

Journal Name:: Coatings

Additional Journal Information:: Journal Name: Coatings Journal Volume: 12 Journal Issue: 6; Journal ID: ISSN 2079-6412

Publisher:: MDPI AG

Country of Publication:: Switzerland

Language:: English

Subject:: 77 NANOSCIENCE AND NANOTECHNOLOGY; multiprobe surface analysis system; UHV-STM; XPS; UPS; ISS; TPD; LEED; nonprecious metals; oxidation; corrosion; localized surface plasmon resonance; galvanic replacement

Citation Formats


                    Okyere, Deborah, Manso, Ryan H., Tong, Xiao, and Chen, Jingyi. Stability of Polyethylene Glycol-Coated Copper Nanoparticles and Their Optical Properties.  Switzerland: N. p., 2022. 
Web.  doi:10.3390/coatings12060776.

Copy to clipboard


                    Okyere, Deborah, Manso, Ryan H., Tong, Xiao, & Chen, Jingyi. Stability of Polyethylene Glycol-Coated Copper Nanoparticles and Their Optical Properties.  Switzerland.  https://doi.org/10.3390/coatings12060776

Copy to clipboard


                    Okyere, Deborah, Manso, Ryan H., Tong, Xiao, and Chen, Jingyi. Sat .  
"Stability of Polyethylene Glycol-Coated Copper Nanoparticles and Their Optical Properties".  Switzerland.  https://doi.org/10.3390/coatings12060776.

Copy to clipboard


                    
@article{osti_1871264,

  title        = {Stability of Polyethylene Glycol-Coated Copper Nanoparticles and Their Optical Properties},

  author       = {Okyere, Deborah and Manso, Ryan H. and Tong, Xiao and Chen, Jingyi},

  abstractNote = {Oxidation is a corrosion reaction where the corroded metal forms an oxide. Prevention of oxidation at the nanoscale is critically important to retain the physicochemical properties of metal nanoparticles. In this work, we studied the stability of polyethylene glycol (PEG) coated copper nanoparticles (PEGylated CuNPs) against oxidation. The freshly-prepared PEGylated CuNPs mainly consist of metallic Cu which are quite stable in air although their surfaces are typically covered with a few monolayers of cuprous oxide. However, they are quickly oxidized in water due to the presence of protons that facilitate oxidation of the cuprous oxide to cupric oxide. PEG with carboxylic acid terminus could slightly delay the oxidation process compared to that with thiol terminus. It was found that a solvent with reducing power such as ethanol could greatly enhance the stability of PEGylated CuNPs by preventing further oxidation of the cuprous oxide to cupric oxide and thus retain the optical properties of CuNPs. The reducing environment also assists the galvanic replacement of these PEGylated CuNPs to form hollow nanoshells; however, they consist of ultra-small particle assemblies due to the co-reduction of gold precursor during the replacement reaction. As a result, these nanoshells do not exhibit strong optical properties in the near-infrared region. This study highlights the importance of solvent effects on PEGylated nonprecious metal nanoparticles against oxidation corrosion and its applications in preserving physicochemical properties of metallic nanostructures.},

  doi          = {10.3390/coatings12060776},

  journal      = {Coatings},

  number       = 6,

  volume       = 12,

  place        = {Switzerland},

  year         = {Sat Jun 04 00:00:00 EDT 2022},

  month        = {Sat Jun 04 00:00:00 EDT 2022}

}

Copy to clipboard

Journal Article:

Free Publicly Available Full Text

Publisher's Version of Record
https://doi.org/10.3390/coatings12060776

Other availability

Search WorldCat to find libraries that may hold this journal

Save / Share:

Export Metadata

Save to My Library

Similar Records in DOE PAGES and OSTI.GOV collections:

PEGylated Nanoceria as Radical Scavenger with Tunable Redox Chemistry

Journal Article Karakoti, Ajay S ; Singh, Sanjay ; Kumar, Amit ; ... - Journal of the American Chemical Society, 131(40):14144-14145

Cerium oxide nanoparticles (CNPs) have shown tremendous potential in various applications such as water gas shift catalysis, chemical mechanical planarization (CMP), solid oxide fuel cells (SOFC), solar cells4 and high temperature oxidation protection coatings1. Recently, CNPs have been demonstrated to protect biological tissues against radiation induced damage, scavenging of superoxide anions, prevention of laser induced retinal damage, reduction of spinal injury in a tissue culture model, prevention of cardiovascular myopathy, pH dependent antioxidant properties, as a tool for immunoassays as well as other inflammatory diseases2. In most biomedical applications it is speculated that nanoceria is a regenerative radical scavenger withmore »« less
https://doi.org/10.1021/ja9051087
Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time

Journal Article Narasimhan, Diwahar ; Collins, Gregory T ; Nance, Mark R ; ... - Mol. Pharmacol.

No small-molecule therapeutic is available to treat cocaine addiction, but enzyme-based therapy to accelerate cocaine hydrolysis in serum has gained momentum. Bacterial cocaine esterase (CocE) is the fastest known native enzyme that hydrolyzes cocaine. However, its lability at 37 C has limited its therapeutic potential. Cross-linking subunits through disulfide bridging is commonly used to stabilize multimeric enzymes. Herein we use structural methods to guide the introduction of two cysteine residues within dimer interface of CocE to facilitate intermolecular disulfide bond formation. The disulfide-crosslinked enzyme displays improved thermostability, particularly when combined with previously described mutations that enhance stability (T172R-G173Q). The newlymore »« less
https://doi.org/10.1124/mol.111.074997
Conjugation of antioxidant molecule to PEGylated NPs for pH dependent drug release

Journal Article Bharti, Shivani ; Kaur, Gurvir ; Gupta, Shikha ; ... - Materials Research Bulletin

Highlights: • Synthesis of Quercetin loaded PEGylated CdSe and PEGylated CdSe/CdS core/shell nanoparticles. • Quercetin quenches the fluorescence intensity of PEGylated nanoparticles. • Conjugation of Quercetin does not alter the spherical morphology of PEGylated nanoparticles. • Effect of pH environment on the optical properties of Quercetin loaded PEGylated nanoparticles. • In vitro release of Quercetin from PEGylated nanoparticles is pH and time dependent. - Abstract: This paper reports the encapsulation of antioxidant molecule Quercetin on PEG-diamine coated nanoparticles (NPs) by aqueous synthesis method to improve it's poor water solubility and stability. Two types of PEGylated NPs (PEGylated CdSe and PEGylatedmore »« less
https://doi.org/10.1016/J.MATERRESBULL.2018.04.020
Predictive high-throughput screening of PEGylated lipids in oligonucleotide-loaded lipid nanoparticles for neuronal gene silencing

Journal Article Sarode, Apoorva ; Fan, Yuchen ; Byrnes, Amy E. ; ... - Nanoscale Advances

Lipid nanoparticles (LNPs) are gaining traction in the field of nucleic acid delivery following the success of two mRNA vaccines against COVID-19. As one of the constituent lipids on LNP surfaces, PEGylated lipids (PEG-lipids) play an important role in defining LNP physicochemical properties and biological interactions. Previous studies indicate that LNP performance is modulated by tuning PEG-lipid parameters including PEG size and architecture, carbon tail type and length, as well as the PEG-lipid molar ratio in LNPs. Owing to these numerous degrees of freedom, a high-throughput approach is necessary to fully understand LNP behavioral trends over a broad range ofmore »« less
https://doi.org/10.1039/D1NA00712B
Chemical modification of lipase with polyethylene glycol

Conference Baillargeon, M W ; Sonnet, P E - Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)

Proteins become soluble in selected organic solvents after covalent attachment of polyethylene glycol (PEG) to the free amino groups. A crude Candida rugosa lipase preparation was coupled with activated PEG to yield a PEG-lipase with both hydrolytic and synthetic activity in aqueous and organic media. The coupling step involved a modification of the procedure of Inada et al. To maintain lipase activity, mild reaction conditions were used: pH 7.5 or 8.0 buffer, 20 minutes reaction at room temperature. Up to 87% of the initial activity is retained in PEG-lipase. The PEG-lipase is soluble in aqueous solution, benzene and trichloroethane. Themore »« less

Similar Records