Surface modification induced cuprous oxide nanoparticle toxicity to duckweed at sub-toxic metal concentrations
Abstract
Nanoparticle capping agents are critical for controlling the growth, oxidation state, and final particle size during aqueous synthesis. However, despite the known phytotoxicity of cetyltrimethylammonium bromide (CTAB) to plants, it is used to synthesize metal oxide nanoparticles of uniform size and with mesoporous structure. Among the few studies that have investigated how CTAB influences nanoparticle toxicity, CTAB has never been identified as the primary cause of nanoparticle toxicity in environmental systems; rather nanoparticle surface charge or morphology was identified as the driver of toxicity in environmentally relevant systems. In the current study, CTAB release from CTAB surface modified Cu2O nanoparticles (SM-Cu2O NPs) inhibited duckweed (Landoltia punctata) growth, even when administered at subtoxic Cu concentrations. Organic ligands, such as humic acid (HA) and ethylenediaminetetraacetic acid (EDTA), lessened growth inhibition associated with exposure to SM-Cu2O NPs, likely through electrostatic and hydrophobic interactions with CTAB. Finally, such results highlight the need for a more holistic approach to nanoparticle surface modification and improved communication between toxicologists and synthetic chemists to develop green alternatives for nanoparticle synthesis.
- Publication Date:
- Research Org.:
- Univ. of California, Davis, CA (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC); USDA
- OSTI Identifier:
- 1801814
- Alternate Identifier(s):
- OSTI ID: 1606053
- Grant/Contract Number:
- SC0008385; 2013-67017-21211
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Science of the Total Environment
- Additional Journal Information:
- Journal Volume: 722; Journal Issue: C; Journal ID: ISSN 0048-9697
- Publisher:
- Elsevier
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 54 ENVIRONMENTAL SCIENCES; environmental sciences & ecology; nanotoxicity; nanoparticles; plant health; heavy metals; fungicides; agriculture
Citation Formats
Rippner, Devin A., Lien, Jennifer, Balla, Hagr, Guo, Ting, Green, Peter G., Young, Thomas M., and Parikh, Sanjai J. Surface modification induced cuprous oxide nanoparticle toxicity to duckweed at sub-toxic metal concentrations. United States: N. p., 2020.
Web. doi:10.1016/j.scitotenv.2020.137607.
Rippner, Devin A., Lien, Jennifer, Balla, Hagr, Guo, Ting, Green, Peter G., Young, Thomas M., & Parikh, Sanjai J. Surface modification induced cuprous oxide nanoparticle toxicity to duckweed at sub-toxic metal concentrations. United States. https://doi.org/10.1016/j.scitotenv.2020.137607
Rippner, Devin A., Lien, Jennifer, Balla, Hagr, Guo, Ting, Green, Peter G., Young, Thomas M., and Parikh, Sanjai J. Thu .
"Surface modification induced cuprous oxide nanoparticle toxicity to duckweed at sub-toxic metal concentrations". United States. https://doi.org/10.1016/j.scitotenv.2020.137607. https://www.osti.gov/servlets/purl/1801814.
@article{osti_1801814,
title = {Surface modification induced cuprous oxide nanoparticle toxicity to duckweed at sub-toxic metal concentrations},
author = {Rippner, Devin A. and Lien, Jennifer and Balla, Hagr and Guo, Ting and Green, Peter G. and Young, Thomas M. and Parikh, Sanjai J.},
abstractNote = {Nanoparticle capping agents are critical for controlling the growth, oxidation state, and final particle size during aqueous synthesis. However, despite the known phytotoxicity of cetyltrimethylammonium bromide (CTAB) to plants, it is used to synthesize metal oxide nanoparticles of uniform size and with mesoporous structure. Among the few studies that have investigated how CTAB influences nanoparticle toxicity, CTAB has never been identified as the primary cause of nanoparticle toxicity in environmental systems; rather nanoparticle surface charge or morphology was identified as the driver of toxicity in environmentally relevant systems. In the current study, CTAB release from CTAB surface modified Cu2O nanoparticles (SM-Cu2O NPs) inhibited duckweed (Landoltia punctata) growth, even when administered at subtoxic Cu concentrations. Organic ligands, such as humic acid (HA) and ethylenediaminetetraacetic acid (EDTA), lessened growth inhibition associated with exposure to SM-Cu2O NPs, likely through electrostatic and hydrophobic interactions with CTAB. Finally, such results highlight the need for a more holistic approach to nanoparticle surface modification and improved communication between toxicologists and synthetic chemists to develop green alternatives for nanoparticle synthesis.},
doi = {10.1016/j.scitotenv.2020.137607},
journal = {Science of the Total Environment},
number = C,
volume = 722,
place = {United States},
year = {Thu Mar 05 00:00:00 EST 2020},
month = {Thu Mar 05 00:00:00 EST 2020}
}
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