skip to main content
DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins

Abstract

Extreme confinement in nanometer sized channels can alter fluid and ion transport in significant ways, leading to significant water flow enhancement and unusual ion correlation effects. These effects are especially pronounced in carbon nanotube porins (CNTPs) that combine strong confinement in the inner lumen of carbon nanotubes with the high slip flow enhancement due to smooth hydrophobic pore walls. For this paper, we have studied ion transport and ion selectivity in 1.5 nm diameter CNTPs embedded in lipid membranes using single nanopore measurement setup. Our data show that CNTPs are weakly cation-selective at pH 7.5 and become non-selective at pH 3.0. Ion conductance of CNTPs exhibits an unusual 2/3 power law scaling with the ion concentration at both neutral and acidic pH values. Coupled Navier-Stokes and Poisson-Nernst-Planck (NS-PNP) simulations and atomistic Molecular Dynamics (MD) simulations reveal that this scaling originates from strong coupling between water and ion transport in these channels. These effects could result in development of a next generation of biomimetic membranes and carbon nanotube-based electroosmotic pumps.

Authors:
 [1];  [2];  [3]; ORCiD logo [3];  [2]; ORCiD logo [1]
  1. Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Univ. of California, Merced, CA (United States)
  2. Univ. of Illinois at Urbana-Champaign, IL (United States)
  3. Northeastern Univ., Boston, MA (United States)
Publication Date:
Research Org.:
Energy Frontier Research Centers (EFRC) (United States). The Center for Enhanced Nanofluidic Transport (CENT); Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA); USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division; National Science Foundation (NSF)
OSTI Identifier:
1657684
Report Number(s):
LLNL-JRNL-780109
Journal ID: ISSN 1936-0851; 974823
Grant/Contract Number:  
AC52-07NA27344; SCW0972; SC0019112; 1710211; AC02-05CH11231; OCI-0725070; ACI-1238993
Resource Type:
Accepted Manuscript
Journal Name:
ACS Nano
Additional Journal Information:
Journal Volume: 13; Journal Issue: 11; Journal ID: ISSN 1936-0851
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; Nanofluidics; Carbon nanotube porins; Ion transport; Slip-flow coupling; Electroosmosis

Citation Formats

Yao, Yun-Chiao, Taqieddin, Amir, Alibakhshi, Mohammad A., Wanunu, Meni, Aluru, Narayana R., and Noy, Aleksandr. Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins. United States: N. p., 2019. Web. https://doi.org/10.1021/acsnano.9b05118.
Yao, Yun-Chiao, Taqieddin, Amir, Alibakhshi, Mohammad A., Wanunu, Meni, Aluru, Narayana R., & Noy, Aleksandr. Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins. United States. https://doi.org/10.1021/acsnano.9b05118
Yao, Yun-Chiao, Taqieddin, Amir, Alibakhshi, Mohammad A., Wanunu, Meni, Aluru, Narayana R., and Noy, Aleksandr. Mon . "Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins". United States. https://doi.org/10.1021/acsnano.9b05118. https://www.osti.gov/servlets/purl/1657684.
@article{osti_1657684,
title = {Strong Electroosmotic Coupling Dominates Ion Conductance of 1.5 nm Diameter Carbon Nanotube Porins},
author = {Yao, Yun-Chiao and Taqieddin, Amir and Alibakhshi, Mohammad A. and Wanunu, Meni and Aluru, Narayana R. and Noy, Aleksandr},
abstractNote = {Extreme confinement in nanometer sized channels can alter fluid and ion transport in significant ways, leading to significant water flow enhancement and unusual ion correlation effects. These effects are especially pronounced in carbon nanotube porins (CNTPs) that combine strong confinement in the inner lumen of carbon nanotubes with the high slip flow enhancement due to smooth hydrophobic pore walls. For this paper, we have studied ion transport and ion selectivity in 1.5 nm diameter CNTPs embedded in lipid membranes using single nanopore measurement setup. Our data show that CNTPs are weakly cation-selective at pH 7.5 and become non-selective at pH 3.0. Ion conductance of CNTPs exhibits an unusual 2/3 power law scaling with the ion concentration at both neutral and acidic pH values. Coupled Navier-Stokes and Poisson-Nernst-Planck (NS-PNP) simulations and atomistic Molecular Dynamics (MD) simulations reveal that this scaling originates from strong coupling between water and ion transport in these channels. These effects could result in development of a next generation of biomimetic membranes and carbon nanotube-based electroosmotic pumps.},
doi = {10.1021/acsnano.9b05118},
journal = {ACS Nano},
number = 11,
volume = 13,
place = {United States},
year = {2019},
month = {11}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record

Citation Metrics:
Cited by: 2 works
Citation information provided by
Web of Science

Save / Share:

Works referenced in this record:

Electrical Energy Storage for the Grid: A Battery of Choices
journal, November 2011


Ion transport in gel and gel–liquid systems for LiClO 4 -doped PMMA at the meso- and nanoscales
journal, January 2017

  • Plett, Timothy; Thai, Mya Le; Cai, Josslyn
  • Nanoscale, Vol. 9, Issue 42
  • DOI: 10.1039/C7NR06719D

Sodium transport in plant cells
journal, May 2000

  • Blumwald, Eduardo; Aharon, Gilad S.; Apse, Maris P.
  • Biochimica et Biophysica Acta (BBA) - Biomembranes, Vol. 1465, Issue 1-2
  • DOI: 10.1016/S0005-2736(00)00135-8

Surface-Charge-Governed Ion Transport in Nanofluidic Channels
journal, July 2004


Nanofluidics, from bulk to interfaces
journal, January 2010

  • Bocquet, Lydéric; Charlaix, Elisabeth
  • Chem. Soc. Rev., Vol. 39, Issue 3
  • DOI: 10.1039/B909366B

Single-file transport of water through membrane channels
journal, January 2018


Water conduction through the hydrophobic channel of a carbon nanotube
journal, November 2001

  • Hummer, G.; Rasaiah, J. C.; Noworyta, J. P.
  • Nature, Vol. 414, Issue 6860
  • DOI: 10.1038/35102535

Enhanced water permeability and tunable ion selectivity in subnanometer carbon nanotube porins
journal, August 2017

  • Tunuguntla, Ramya H.; Henley, Robert Y.; Yao, Yun-Chiao
  • Science, Vol. 357, Issue 6353
  • DOI: 10.1126/science.aan2438

Fast Mass Transport Through Sub-2-Nanometer Carbon Nanotubes
journal, May 2006


Massive radius-dependent flow slippage in carbon nanotubes
journal, September 2016

  • Secchi, Eleonora; Marbach, Sophie; Niguès, Antoine
  • Nature, Vol. 537, Issue 7619
  • DOI: 10.1038/nature19315

Giant osmotic energy conversion measured in a single transmembrane boron nitride nanotube
journal, February 2013

  • Siria, Alessandro; Poncharal, Philippe; Biance, Anne-Laure
  • Nature, Vol. 494, Issue 7438
  • DOI: 10.1038/nature11876

Size effect in ion transport through angstrom-scale slits
journal, October 2017


Anomalously low dielectric constant of confined water
journal, June 2018


Scaling Behavior for Ionic Transport and its Fluctuations in Individual Carbon Nanotubes
journal, April 2016


Salt Dependence of Ion Transport and DNA Translocation through Solid-State Nanopores
journal, January 2006

  • Smeets, Ralph M. M.; Keyser, Ulrich F.; Krapf, Diego
  • Nano Letters, Vol. 6, Issue 1
  • DOI: 10.1021/nl052107w

Single-Walled Carbon Nanotubes: Mimics of Biological Ion Channels
journal, January 2017


Water and ion transport through functionalised carbon nanotubes: implications for desalination technology
journal, January 2011


Enhanced flow in carbon nanotubes
journal, November 2005

  • Majumder, Mainak; Chopra, Nitin; Andrews, Rodney
  • Nature, Vol. 438, Issue 7064
  • DOI: 10.1038/438044a

Electrophoretically induced aqueous flow through single-walled carbon nanotube membranes
journal, January 2012


Stochastic transport through carbon nanotubes in lipid bilayers and live cell membranes
journal, October 2014

  • Geng, Jia; Kim, Kyunghoon; Zhang, Jianfei
  • Nature, Vol. 514, Issue 7524
  • DOI: 10.1038/nature13817

Synthesis, lipid membrane incorporation, and ion permeability testing of carbon nanotube porins
journal, September 2016

  • Tunuguntla, Ramya H.; Escalada, Artur; A. Frolov, Vadim
  • Nature Protocols, Vol. 11, Issue 10
  • DOI: 10.1038/nprot.2016.119

Analysis of ionic conductance of carbon nanotubes
journal, November 2016


Observation of ionic Coulomb blockade in nanopores
journal, March 2016

  • Feng, Jiandong; Liu, Ke; Graf, Michael
  • Nature Materials, Vol. 15, Issue 8
  • DOI: 10.1038/nmat4607

Modeling the conductance and DNA blockade of solid-state nanopores
journal, July 2011


Coherence Resonance in a Single-Walled Carbon Nanotube Ion Channel
journal, September 2010


Chemisorption of Hydroxide on 2D Materials from DFT Calculations: Graphene versus Hexagonal Boron Nitride
journal, November 2016

  • Grosjean, Benoit; Pean, Clarisse; Siria, Alessandro
  • The Journal of Physical Chemistry Letters, Vol. 7, Issue 22
  • DOI: 10.1021/acs.jpclett.6b02248

Crossover of the Power-Law Exponent for Carbon Nanotube Conductivity as a Function of Salinity
journal, February 2018

  • Uematsu, Yuki; Netz, Roland R.; Bocquet, Lydéric
  • The Journal of Physical Chemistry B, Vol. 122, Issue 11
  • DOI: 10.1021/acs.jpcb.8b01975

Osmotic Transport across Surface Functionalized Carbon Nanotube Membrane
journal, October 2018


Role of charge regulation and flow slip in the ionic conductance of nanopores: An analytical approach
journal, July 2018


Highly efficient electroosmotic flow through functionalized carbon nanotube membranes
journal, January 2011

  • Wu, Ji; Gerstandt, Karen; Majumder, Mainak
  • Nanoscale, Vol. 3, Issue 8
  • DOI: 10.1039/c1nr10303b

Electroosmotic Pumps Fabricated From Porous Silicon Membranes
journal, June 2006

  • Yao, S.; Myers, A. M.; Posner, J. D.
  • Journal of Microelectromechanical Systems, Vol. 15, Issue 3
  • DOI: 10.1109/JMEMS.2006.876796

1/f noise in membranes
journal, July 1978

  • Neumcke, B.
  • Biophysics of Structure and Mechanism, Vol. 4, Issue 3
  • DOI: 10.1007/BF02426084

Membrane noise
journal, January 1974


An upper estimate for 1/ƒ noise intensity in ionic conductors from experiments with a molecular microcontact
journal, September 1987


1/⨍ noise in continuous thin gold films
journal, December 1969


Noise in solid-state nanopores
journal, January 2008

  • Smeets, R. M. M.; Keyser, U. F.; Dekker, N. H.
  • Proceedings of the National Academy of Sciences, Vol. 105, Issue 2
  • DOI: 10.1073/pnas.0705349105

Understanding anomalous current–voltage characteristics in microchannel–nanochannel interconnect devices
journal, October 2012

  • Nandigana, Vishal V. R.; Aluru, N. R.
  • Journal of Colloid and Interface Science, Vol. 384, Issue 1
  • DOI: 10.1016/j.jcis.2012.06.004

Single-layer MoS2 nanopores as nanopower generators
journal, July 2016


Gmsh: A 3-D finite element mesh generator with built-in pre- and post-processing facilities
journal, September 2009

  • Geuzaine, Christophe; Remacle, Jean-François
  • International Journal for Numerical Methods in Engineering, Vol. 79, Issue 11
  • DOI: 10.1002/nme.2579

Fast Parallel Algorithms for Short-Range Molecular Dynamics
journal, March 1995


VMD: Visual molecular dynamics
journal, February 1996


PACKMOL: A package for building initial configurations for molecular dynamics simulations
journal, October 2009

  • Martínez, L.; Andrade, R.; Birgin, E. G.
  • Journal of Computational Chemistry, Vol. 30, Issue 13
  • DOI: 10.1002/jcc.21224

A unified formulation of the constant temperature molecular dynamics methods
journal, July 1984

  • Nosé, Shuichi
  • The Journal of Chemical Physics, Vol. 81, Issue 1
  • DOI: 10.1063/1.447334

Canonical dynamics: Equilibrium phase-space distributions
journal, March 1985