A Fourier transform infrared spectroscopy‐ based method for tracking diffusion in organogels
Abstract
Organogels possess characteristics that make them promising materials for enhancing our understanding of nanostructure-diffusion relationships in gels and for use in diffusion-centered applications including drug delivery and nanoreactor media. Unlike hydrogels, however, there are no well-recognized techniques for measuring the fundamental diffusion parameter of diffusivity, D, in organogels. The present work establishes a technique for measuring D based upon Fourier-transform infrared spectroscopy. Physically crosslinked gels composed of poly[styrene-b-(ethylene-butylene)-b-styrene] and aliphatic mineral oil are used to showcase the new technique's capability. Diffusivity of unimers-oleic acid-and reverse micelles-sodium dioctyl sulfosuccinate (AOT)-within as-prepared and preswollen gels is quantified and resultant values are commensurate with studies of unimer and micelle diffusion in hydrogels. The case of AOT diffusion is further validated through small-angle X-ray scattering analysis, which is in close agreement (<20% difference).
- Authors:
-
[1];
- Department of Chemical EngineeringBucknell University Lewisburg Pennsylvania USA
- X‐ray Science Division, Argonne National Laboratory Lemont Illinois USA
- Publication Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC), Basic Energy Sciences (BES); National Science Foundation (NSF)
- OSTI Identifier:
- 1631203
- Alternate Identifier(s):
- OSTI ID: 1631207; OSTI ID: 1658838
- Grant/Contract Number:
- AC02-06CH11357; 1904047
- Resource Type:
- Published Article
- Journal Name:
- Journal of Polymer Science
- Additional Journal Information:
- Journal Name: Journal of Polymer Science Journal Volume: 58 Journal Issue: 12; Journal ID: ISSN 2642-4150
- Publisher:
- Wiley Blackwell (John Wiley & Sons)
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; block copolymers; diffusion; infrared spectroscopy; organogels
Citation Formats
Mineart, Kenneth P., Walker, William W., Mogollon‐Santiana, Joaquin, and Lee, Byeongdu. A Fourier transform infrared spectroscopy‐ based method for tracking diffusion in organogels. United States: N. p., 2020.
Web. doi:10.1002/pol.20200144.
Mineart, Kenneth P., Walker, William W., Mogollon‐Santiana, Joaquin, & Lee, Byeongdu. A Fourier transform infrared spectroscopy‐ based method for tracking diffusion in organogels. United States. https://doi.org/10.1002/pol.20200144
Mineart, Kenneth P., Walker, William W., Mogollon‐Santiana, Joaquin, and Lee, Byeongdu. Fri .
"A Fourier transform infrared spectroscopy‐ based method for tracking diffusion in organogels". United States. https://doi.org/10.1002/pol.20200144.
@article{osti_1631203,
title = {A Fourier transform infrared spectroscopy‐ based method for tracking diffusion in organogels},
author = {Mineart, Kenneth P. and Walker, William W. and Mogollon‐Santiana, Joaquin and Lee, Byeongdu},
abstractNote = {Organogels possess characteristics that make them promising materials for enhancing our understanding of nanostructure-diffusion relationships in gels and for use in diffusion-centered applications including drug delivery and nanoreactor media. Unlike hydrogels, however, there are no well-recognized techniques for measuring the fundamental diffusion parameter of diffusivity, D, in organogels. The present work establishes a technique for measuring D based upon Fourier-transform infrared spectroscopy. Physically crosslinked gels composed of poly[styrene-b-(ethylene-butylene)-b-styrene] and aliphatic mineral oil are used to showcase the new technique's capability. Diffusivity of unimers-oleic acid-and reverse micelles-sodium dioctyl sulfosuccinate (AOT)-within as-prepared and preswollen gels is quantified and resultant values are commensurate with studies of unimer and micelle diffusion in hydrogels. The case of AOT diffusion is further validated through small-angle X-ray scattering analysis, which is in close agreement (<20% difference).},
doi = {10.1002/pol.20200144},
journal = {Journal of Polymer Science},
number = 12,
volume = 58,
place = {United States},
year = {Fri May 29 00:00:00 EDT 2020},
month = {Fri May 29 00:00:00 EDT 2020}
}
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Works referenced in this record:
Diffusion of Polyelectrolytes in Polyelectrolyte Gels
journal, October 2017
- Rahalkar, Anand; Muthukumar, Murugappan
- Macromolecules, Vol. 50, Issue 20
Application of organogels as oral controlled release formulations of hydrophilic drugs
journal, October 2012
- Iwanaga, Kazunori; Kawai, Mineo; Miyazaki, Makoto
- International Journal of Pharmaceutics, Vol. 436, Issue 1-2
Macromolecule Sorption and Diffusion in HEMA/MAA Hydrogels
journal, December 2013
- Liu, D. E.; Kotsmar, C.; Nguyen, F.
- Industrial & Engineering Chemistry Research, Vol. 52, Issue 50
A microfluidic method to measure small molecule diffusion in hydrogels
journal, February 2014
- Evans, Stephanie M.; Litzenberger, Andrew L.; Ellenberger, Anne E.
- Materials Science and Engineering: C, Vol. 35
Thermoplastic elastomer gels. I. Effects of composition and processing on morphology and gel behavior
journal, September 1998
- Laurer, Jonathan H.; Mulling, James F.; Khan, Saad A.
- Journal of Polymer Science Part B: Polymer Physics, Vol. 36, Issue 13
Designing hydrogels for controlled drug delivery
journal, October 2016
- Li, Jianyu; Mooney, David J.
- Nature Reviews Materials, Vol. 1, Issue 12
Extended release of dexamethasone from silicone-hydrogel contact lenses containing vitamin E
journal, November 2010
- Kim, Jinah; Peng, Cheng-Chun; Chauhan, Anuj
- Journal of Controlled Release, Vol. 148, Issue 1
Diffusion of macromolecules in a polymer hydrogel: from microscopic to macroscopic scales
journal, January 2016
- Sandrin, D.; Wagner, D.; Sitta, C. E.
- Physical Chemistry Chemical Physics, Vol. 18, Issue 18
Characterization of organogel as a novel oral controlled release formulation for lipophilic compounds
journal, March 2010
- Iwanaga, Kazunori; Sumizawa, Toru; Miyazaki, Makoto
- International Journal of Pharmaceutics, Vol. 388, Issue 1-2
Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics
journal, March 2010
- Brandl, Ferdinand; Kastner, Fritz; Gschwind, Ruth M.
- Journal of Controlled Release, Vol. 142, Issue 2
Evidence for a Critical Micelle Concentration of Surfactants in Hydrocarbon Solvents
journal, February 2013
- Smith, Gregory N.; Brown, Paul; Rogers, Sarah E.
- Langmuir, Vol. 29, Issue 10
Charge transport by inverse micelles in non-polar media
journal, October 2017
- Strubbe, Filip; Neyts, Kristiaan
- Journal of Physics: Condensed Matter, Vol. 29, Issue 45
Organogels and their use in drug delivery — A review
journal, February 2008
- Vintiloiu, Anda; Leroux, Jean-Christophe
- Journal of Controlled Release, Vol. 125, Issue 3
Thermoplastic elastomer gels. II. Effects of composition and temperature on morphology and gel rheology
journal, October 1998
- Laurer, J. H.; Mulling, J. F.; Khan, S. A.
- Journal of Polymer Science Part B: Polymer Physics, Vol. 36, Issue 14
Modified-release topical hydrogels: a ten-year review
journal, April 2019
- Croisfelt, Fernanda Machado; Tundisi, Louise Lacalendola; Ataide, Janaína Artem
- Journal of Materials Science, Vol. 54, Issue 16
Polymer Actuators Using Ion-Gel Electrolytes Prepared by Self-Assembly of ABA-Triblock Copolymers
journal, December 2011
- Imaizumi, Satoru; Kokubo, Hisashi; Watanabe, Masayoshi
- Macromolecules, Vol. 45, Issue 1
Preparation of thermosensitive polymeric organogels and their drug release behaviors
journal, February 2010
- Tokuyama, Hideaki; Kato, Yuya
- European Polymer Journal, Vol. 46, Issue 2
Self-diffusion coefficients of lithium, anion, polymer, and solvent in polymer gel electrolytes measured using 7Li, 19F, and 1H pulsed-gradient spin-echo NMR
journal, January 2000
- Hayamizu, Kikuko; Aihara, Yuichi; Arai, Shigemasa
- Electrochimica Acta, Vol. 45, Issue 8-9
Generation current of charged micelles in nonaqueous liquids: Measurements and simulations
journal, August 2006
- Strubbe, Filip; Verschueren, Alwin R. M.; Schlangen, Luc J. M.
- Journal of Colloid and Interface Science, Vol. 300, Issue 1
Characterization and biocompatibility of organogels based on l-alanine for parenteral drug delivery implants
journal, November 2005
- Motulsky, Aude; Lafleur, Michel; Couffin-Hoarau, Anne-Claude
- Biomaterials, Vol. 26, Issue 31
Enhanced Biomimetic Performance of Ionic Polymer-Metal Composite Actuators Prepared with Nanostructured Block Ionomers
journal, November 2011
- Vargantwar, Pruthesh H.; Roskov, Kristen E.; Ghosh, Tushar K.
- Macromolecular Rapid Communications, Vol. 33, Issue 1
The transport of water in a tetrafunctional epoxy resin by near-infrared Fourier transform spectroscopy
journal, January 2000
- Musto, P.; Mascia, L.; Ragosta, G.
- Polymer, Vol. 41, Issue 2
Diffusion of proteins and nonionic micelles in agarose gels by holographic interferometry
journal, January 1997
- Kong, Donna D.; Kosar, T. Fettah; Dungan, Stephanie R.
- AIChE Journal, Vol. 43, Issue 1
Self-Diffusion and Mutual Diffusion of Small Molecules in High-Set Curdlan Hydrogels Studied by 31 P NMR
journal, July 2009
- Gagnon, Marc-André; Lafleur, Michel
- The Journal of Physical Chemistry B, Vol. 113, Issue 27
Fourier Transform Infrared Investigation on Water States and the Conformations of Aerosol-OT in Reverse Microemulsions
journal, June 2002
- Zhou, Guo-Wei; Li, Gan-Zuo; Chen, Wen-Jun
- Langmuir, Vol. 18, Issue 12
Near infrared (NIR) spectroscopy compared with thermogravimetric analysis as a tool for on-line prediction of water diffusion in polyamide 6,6
journal, January 2002
- Camacho, Walker; Hedenqvist, M?S; Karlsson, Sigbritt
- Polymer International, Vol. 51, Issue 12
Organogels, promising drug delivery systems: an update of state-of-the-art and recent applications
journal, February 2018
- Esposito, Cloé L.; Kirilov, Plamen; Roullin, V. Gaëlle
- Journal of Controlled Release, Vol. 271
Controlled release of functional proteins through designer self-assembling peptide nanofiber hydrogel scaffold
journal, March 2009
- Koutsopoulos, S.; Unsworth, L. D.; Nagai, Y.
- Proceedings of the National Academy of Sciences, Vol. 106, Issue 12
Water diffusion with temperature enabling predictions for sorption and transport behavior in thermoset materials
journal, September 2018
- Linde, Erik; Giron, Nicholas H.; Celina, Mathew C.
- Polymer, Vol. 153
Investigation of Various Types of Inverse Micelles in Nonpolar Liquids Using Transient Current Measurements
journal, October 2014
- Karvar, Masoumeh; Strubbe, Filip; Beunis, Filip
- Langmuir, Vol. 30, Issue 41
Photophysical and photochemical processes in 3D self-assembled gels as confined microenvironments
journal, January 2015
- Pérez-Ruiz, Raúl; Díaz Díaz, David
- Soft Matter, Vol. 11, Issue 26
Quantifying diffusion in mucosal systems by pulsed-gradient spin-echo NMR
journal, December 2008
- Occhipinti, Paola; Griffiths, Peter C.
- Advanced Drug Delivery Reviews, Vol. 60, Issue 15
Solute Diffusion within Hydrogels. Mechanisms and Models
journal, November 1998
- Amsden, Brian
- Macromolecules, Vol. 31, Issue 23
Adenosine triphosphate diffusion through poly(ethylene glycol) diacrylate hydrogels can be tuned by cross-link density as measured by PFG-NMR
journal, June 2017
- Majer, Günter; Southan, Alexander
- The Journal of Chemical Physics, Vol. 146, Issue 22
Pulse-Gradient Spin-Echo 1 H, 7 Li, and 19 F NMR Diffusion and Ionic Conductivity Measurements of 14 Organic Electrolytes Containing LiN(SO 2 CF 3 ) 2
journal, January 1999
- Hayamizu, Kikuko; Aihara, Yuichi; Arai, Shigemasa
- The Journal of Physical Chemistry B, Vol. 103, Issue 3