Cross talk between RNA N6‐methyladenosine methyltransferase‐like 3 and miR‐186 regulates hepatoblastoma progression through Wnt/β‐catenin signalling pathway

doi:10.1111/cpr.12768

Title: Cross talk between RNA N6‐methyladenosine methyltransferase‐like 3 and miR‐186 regulates hepatoblastoma progression through Wnt/β‐catenin signalling pathway

Authors:

Cui, Xichun ^[1]; Wang, Zhifang ^[2]; Li, Jianhao ^[3]; Zhu, Jianming ^[3]; Ren, Zhigang ^[3]; Zhang, Dandan ^[4]; Zhao, Wei ^[1]; Fan, Yingzhong ^[1]; Zhang, Da ^[1];

^[3]

Pediatric Surgery Department The First Affiliated Hospital of Zhengzhou University Zhengzhou China
Endocrinology Department The First Affiliated Hospital of Zhengzhou University Zhengzhou China
Precision Medicine Center The First Affiliated Hospital of Zhengzhou University Zhengzhou China
Pathology Department The First Affiliated Hospital of Zhengzhou University Zhengzhou China

Publication Date:: 2020-03-01

Sponsoring Org.:: USDOE Office of Electricity (OE), Advanced Grid Research & Development. Power Systems Engineering Research

OSTI Identifier:: 1593197

Alternate Identifier(s):: OSTI ID: 1593199

Grant/Contract Number:: 2018YFC2000500; 2017M610463; 2018M632814; NELIMSA2018P03

Resource Type:: Published Article

Journal Name:: Cell Proliferation

Additional Journal Information:: Journal Name: Cell Proliferation Journal Volume: 53 Journal Issue: 3; Journal ID: ISSN 0960-7722

Publisher:: Wiley-Blackwell

Country of Publication:: United Kingdom

Language:: English

Citation Formats


                    Cui, Xichun, Wang, Zhifang, Li, Jianhao, Zhu, Jianming, Ren, Zhigang, Zhang, Dandan, Zhao, Wei, Fan, Yingzhong, Zhang, Da, and Sun, Ranran. Cross talk between RNA N6‐methyladenosine methyltransferase‐like 3 and miR‐186 regulates hepatoblastoma progression through Wnt/β‐catenin signalling pathway.  United Kingdom: N. p., 2020. 
        Web.  doi:10.1111/cpr.12768.

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                    Cui, Xichun, Wang, Zhifang, Li, Jianhao, Zhu, Jianming, Ren, Zhigang, Zhang, Dandan, Zhao, Wei, Fan, Yingzhong, Zhang, Da, & Sun, Ranran. Cross talk between RNA N6‐methyladenosine methyltransferase‐like 3 and miR‐186 regulates hepatoblastoma progression through Wnt/β‐catenin signalling pathway.  United Kingdom.  doi:10.1111/cpr.12768.

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                    Cui, Xichun, Wang, Zhifang, Li, Jianhao, Zhu, Jianming, Ren, Zhigang, Zhang, Dandan, Zhao, Wei, Fan, Yingzhong, Zhang, Da, and Sun, Ranran. Sun .  
        "Cross talk between RNA N6‐methyladenosine methyltransferase‐like 3 and miR‐186 regulates hepatoblastoma progression through Wnt/β‐catenin signalling pathway".  United Kingdom.  doi:10.1111/cpr.12768.

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@article{osti_1593197,

  title        = {Cross talk between RNA N6‐methyladenosine methyltransferase‐like 3 and miR‐186 regulates hepatoblastoma progression through Wnt/β‐catenin signalling pathway},

  author       = {Cui, Xichun and Wang, Zhifang and Li, Jianhao and Zhu, Jianming and Ren, Zhigang and Zhang, Dandan and Zhao, Wei and Fan, Yingzhong and Zhang, Da and Sun, Ranran},

  abstractNote = {},

  doi          = {10.1111/cpr.12768},

  journal      = {Cell Proliferation},

  number       = 3,

  volume       = 53,

  place        = {United Kingdom},

  year         = {2020},

  month        = {3}

}

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DOI: 10.1111/cpr.12768

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Title: Cross talk between RNA N6‐methyladenosine methyltransferase‐like 3 and miR‐186 regulates hepatoblastoma progression through Wnt/β‐catenin signalling pathway

Citation Formats

Critical Enzymatic Functions of FTO in Obesity and Cancer journal, July 2018

Apoptosis induction in K562 human myelogenous leukaemia cells is connected to the modulation of Wnt/β-catenin signalling by BHX, a novel pyrazoline derivative journal, January 2018

Caught up in a Wnt storm: Wnt signaling in cancer journal, June 2003

miRNA-30e regulates abnormal differentiation of small intestinal epithelial cells in diabetic mice by downregulating Dll4 expression journal, January 2016

Dynamic RNA modifications in disease journal, June 2014

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification journal, February 2018

N6-methyladenosine-dependent regulation of messenger RNA stability journal, November 2013

Wnt signaling and telomerase activation of hepatoblastoma: correlation with chemosensitivity and surgical resectability journal, December 2011

Natural Killer–Derived Exosomal miR-186 Inhibits Neuroblastoma Growth and Immune Escape Mechanisms journal, December 2018

MicroRNA-17, MicroRNA-19b, MicroRNA-146a, MicroRNA-302d Expressions in Hepatoblastoma and Clinical Importance journal, January 2019

Management of hepatoblastoma: an update journal, January 2014

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells journal, May 2016

RUNX3 regulates hepatocellular carcinoma cell metastasis via targeting miR-186/E-cadherin/EMT pathway journal, June 2017

MicroRNA-186 suppresses cell proliferation and metastasis through targeting MAP3K2 in non-small cell lung cancer journal, July 2016

N6-methyladenosine marks primary microRNAs for processing journal, March 2015

Wnt signaling and hepatocarcinogenesis: The hepatoblastoma model journal, February 2011

RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2 journal, April 2018

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA journal, March 2016

Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing journal, June 2016

Reduced m6A mRNA methylation is correlated with the progression of human cervical cancer journal, October 2017

miR‐186 inhibits proliferation, migration, and epithelial‐mesenchymal transition in breast cancer cells by targeting Twist1 journal, December 2018

Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway journal, September 2019

Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer journal, December 2017

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism journal, May 2018

Diagnostic and prognostic values of serum exosomal microRNA-21 in children with hepatoblastoma: a Chinese population-based study journal, September 2016

β-catenin regulates IRF3-mediated innate immune signalling in colorectal cancer journal, July 2018

MicroRNA expression and its clinical implications in Ewing's sarcoma journal, December 2014

Increased N6-methyladenosine causes infertility is associated with FTO expression journal, March 2018

METTL13 is downregulated in bladder carcinoma and suppresses cell proliferation, migration and invasion journal, January 2016

Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential journal, May 2016

MeT-DB V2.0: elucidating context-specific functions of N6-methyl-adenosine methyltranscriptome journal, November 2017

MiR-186 suppresses the growth and metastasis of bladder cancer by targeting NSBP1 journal, August 2015

METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N 6 ‐methyladenosine‐dependent primary MicroRNA processing journal, December 2016

HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g journal, February 2018

The Role of MicroRNAs in Hepatoblastoma Tumors journal, March 2019

MicroRNA-492 is processed from the keratin 19 gene and up-regulated in metastatic hepatoblastoma journal, February 2011

MicroRNA-186 targets Yes-associated protein 1 to inhibit Hippo signaling and tumorigenesis in hepatocellular carcinoma journal, March 2016

Effects of Wnt/β-catenin signalling on proliferation and differentiation of apical papilla stem cells: Effects of Wnt/β-catenin signalling journal, January 2012

The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network journal, January 2019

Long Noncoding RNA ANRIL Promotes Cervical Cancer Development by Acting as a Sponge of miR-186 journal, April 2018

m6A Facilitates eIF4F-Independent mRNA Translation journal, November 2017

Novel Advances in Understanding of Molecular Pathogenesis of Hepatoblastoma: A Wnt/β-Catenin Perspective journal, February 2017

Critical Enzymatic Functions of FTO in Obesity and Cancer
journal, July 2018

Apoptosis induction in K562 human myelogenous leukaemia cells is connected to the modulation of Wnt/β-catenin signalling by BHX, a novel pyrazoline derivative
journal, January 2018

Caught up in a Wnt storm: Wnt signaling in cancer
journal, June 2003

miRNA-30e regulates abnormal differentiation of small intestinal epithelial cells in diabetic mice by downregulating Dll4 expression
journal, January 2016

Dynamic RNA modifications in disease
journal, June 2014

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification
journal, February 2018

N6-methyladenosine-dependent regulation of messenger RNA stability
journal, November 2013

Wnt signaling and telomerase activation of hepatoblastoma: correlation with chemosensitivity and surgical resectability
journal, December 2011

Natural Killer–Derived Exosomal miR-186 Inhibits Neuroblastoma Growth and Immune Escape Mechanisms
journal, December 2018

MicroRNA-17, MicroRNA-19b, MicroRNA-146a, MicroRNA-302d Expressions in Hepatoblastoma and Clinical Importance
journal, January 2019

Management of hepatoblastoma: an update
journal, January 2014

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
journal, May 2016

RUNX3 regulates hepatocellular carcinoma cell metastasis via targeting miR-186/E-cadherin/EMT pathway
journal, June 2017

MicroRNA-186 suppresses cell proliferation and metastasis through targeting MAP3K2 in non-small cell lung cancer
journal, July 2016

N6-methyladenosine marks primary microRNAs for processing
journal, March 2015

Wnt signaling and hepatocarcinogenesis: The hepatoblastoma model
journal, February 2011

RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2
journal, April 2018

Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
journal, March 2016

Nuclear m 6 A Reader YTHDC1 Regulates mRNA Splicing
journal, June 2016

Reduced m⁶A mRNA methylation is correlated with the progression of human cervical cancer
journal, October 2017

miR‐186 inhibits proliferation, migration, and epithelial‐mesenchymal transition in breast cancer cells by targeting Twist1
journal, December 2018

Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway
journal, September 2019

Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer
journal, December 2017

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism
journal, May 2018

Diagnostic and prognostic values of serum exosomal microRNA-21 in children with hepatoblastoma: a Chinese population-based study
journal, September 2016

β-catenin regulates IRF3-mediated innate immune signalling in colorectal cancer
journal, July 2018

MicroRNA expression and its clinical implications in Ewing's sarcoma
journal, December 2014

Increased N6-methyladenosine causes infertility is associated with FTO expression
journal, March 2018

METTL13 is downregulated in bladder carcinoma and suppresses cell proliferation, migration and invasion
journal, January 2016

Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential
journal, May 2016

MeT-DB V2.0: elucidating context-specific functions of N6-methyl-adenosine methyltranscriptome
journal, November 2017

MiR-186 suppresses the growth and metastasis of bladder cancer by targeting NSBP1
journal, August 2015

METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulating N 6 ‐methyladenosine‐dependent primary MicroRNA processing
journal, December 2016

HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g
journal, February 2018

The Role of MicroRNAs in Hepatoblastoma Tumors
journal, March 2019

MicroRNA-492 is processed from the keratin 19 gene and up-regulated in metastatic hepatoblastoma
journal, February 2011

MicroRNA-186 targets Yes-associated protein 1 to inhibit Hippo signaling and tumorigenesis in hepatocellular carcinoma
journal, March 2016

Effects of Wnt/β-catenin signalling on proliferation and differentiation of apical papilla stem cells: Effects of Wnt/β-catenin signalling
journal, January 2012

The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network
journal, January 2019

Long Noncoding RNA ANRIL Promotes Cervical Cancer Development by Acting as a Sponge of miR-186
journal, April 2018

m6A Facilitates eIF4F-Independent mRNA Translation
journal, November 2017

Novel Advances in Understanding of Molecular Pathogenesis of Hepatoblastoma: A Wnt/β-Catenin Perspective
journal, February 2017