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Title: Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality

Authors:
 [1];  [2];  [1];  [1]; ORCiD logo [1];  [1];  [3]; ORCiD logo [4]; ORCiD logo [1]
  1. U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Product Quality, Office of Biotechnology Products, Division of Biotechnology Review and Research II Silver Spring Maryland
  2. U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Testing and Research, Division of Product Quality Research Silver Spring Maryland
  3. U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Product Quality, Office of Biotechnology Products, Division of Biotechnology Review and Research II Silver Spring Maryland, Sartorius Stedim North America IncCorporate Research Bohemia NY
  4. Department of Chemical EngineeringUniversity of Massachusetts Lowell Massachusetts
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1564340
Alternate Identifier(s):
OSTI ID: 1564341
Resource Type:
Published Article
Journal Name:
Biotechnology Progress
Additional Journal Information:
Journal Name: Biotechnology Progress; Journal ID: ISSN 8756-7938
Publisher:
Wiley Blackwell (John Wiley & Sons)
Country of Publication:
United States
Language:
English

Citation Formats

Powers, David N., Wang, Yifan, Fratz‐Berilla, Erica J., Velugula‐Yellela, Sai Rashmika, Chavez, Brittany, Angart, Phillip, Trunfio, Nicholas, Yoon, Seongkyu, and Agarabi, Cyrus. Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality. United States: N. p., 2019. Web. doi:10.1002/btpr.2894.
Powers, David N., Wang, Yifan, Fratz‐Berilla, Erica J., Velugula‐Yellela, Sai Rashmika, Chavez, Brittany, Angart, Phillip, Trunfio, Nicholas, Yoon, Seongkyu, & Agarabi, Cyrus. Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality. United States. doi:10.1002/btpr.2894.
Powers, David N., Wang, Yifan, Fratz‐Berilla, Erica J., Velugula‐Yellela, Sai Rashmika, Chavez, Brittany, Angart, Phillip, Trunfio, Nicholas, Yoon, Seongkyu, and Agarabi, Cyrus. Wed . "Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality". United States. doi:10.1002/btpr.2894.
@article{osti_1564340,
title = {Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality},
author = {Powers, David N. and Wang, Yifan and Fratz‐Berilla, Erica J. and Velugula‐Yellela, Sai Rashmika and Chavez, Brittany and Angart, Phillip and Trunfio, Nicholas and Yoon, Seongkyu and Agarabi, Cyrus},
abstractNote = {},
doi = {10.1002/btpr.2894},
journal = {Biotechnology Progress},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {8}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record
DOI: 10.1002/btpr.2894

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