Cytoprotective metal-organic frameworks for anaerobic bacteria
Abstract
We report a strategy to uniformly wrap Morella thermoacetica bacteria with a metal-organic framework (MOF) monolayer of nanometer thickness for cytoprotection in artificial photosynthesis. The catalytic activity of the MOF enclosure toward decomposition of reactive oxygen species (ROS) reduces the death of strictly anaerobic bacteria by fivefold in the presence of 21% O2, and enables the cytoprotected bacteria to continuously produce acetate from CO2 fixation under oxidative stress. The high definition of the MOF–bacteria interface involving direct bonding between phosphate units on the cell surface and zirconium clusters on MOF monolayer, provides for enhancement of life throughout reproduction. The dynamic nature of the MOF wrapping allows for cell elongation and separation, including spontaneous covering of the newly grown cell surface. Finally, the open-metal sites on the zirconium clusters lead to 600 times more efficient ROS decomposition compared with zirconia nanoparticles.
- Authors:
-
- Univ. of California, Berkeley, CA (United States). Dept. of Chemistry; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials Sciences Division; Kavli Energy NanoSciences Inst., Berkeley, CA (United States)
- Univ. of California, Berkeley, CA (United States). Dept. of Chemistry
- Univ. of California, Berkeley, CA (United States). Dept. of Chemistry; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials Sciences Division; King Abdulaziz City of Science and Technology, Riyadh (Saudi Arabia)
- Univ. of California, Berkeley, CA (United States). Dept. of Chemistry; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Materials Sciences Division; Univ. of California, Berkeley, CA (United States). Dept. of Materials Science and Engineering; Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). fChemical Sciences Division
- Publication Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC); National Aeronautics and Space Administration (NASA)
- OSTI Identifier:
- 1561896
- Grant/Contract Number:
- AC02-05CH11231
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Proceedings of the National Academy of Sciences of the United States of America
- Additional Journal Information:
- Journal Volume: 115; Journal Issue: 42; Journal ID: ISSN 0027-8424
- Publisher:
- National Academy of Sciences, Washington, DC (United States)
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; cell wrapping; metal-organic frameworks; anaerobic bacteria; artificial photosynthesis; reactive oxygen species
Citation Formats
Ji, Zhe, Zhang, Hao, Liu, Hao, Yaghi, Omar M., and Yang, Peidong. Cytoprotective metal-organic frameworks for anaerobic bacteria. United States: N. p., 2018.
Web. doi:10.1073/pnas.1808829115.
Ji, Zhe, Zhang, Hao, Liu, Hao, Yaghi, Omar M., & Yang, Peidong. Cytoprotective metal-organic frameworks for anaerobic bacteria. United States. https://doi.org/10.1073/pnas.1808829115
Ji, Zhe, Zhang, Hao, Liu, Hao, Yaghi, Omar M., and Yang, Peidong. Mon .
"Cytoprotective metal-organic frameworks for anaerobic bacteria". United States. https://doi.org/10.1073/pnas.1808829115. https://www.osti.gov/servlets/purl/1561896.
@article{osti_1561896,
title = {Cytoprotective metal-organic frameworks for anaerobic bacteria},
author = {Ji, Zhe and Zhang, Hao and Liu, Hao and Yaghi, Omar M. and Yang, Peidong},
abstractNote = {We report a strategy to uniformly wrap Morella thermoacetica bacteria with a metal-organic framework (MOF) monolayer of nanometer thickness for cytoprotection in artificial photosynthesis. The catalytic activity of the MOF enclosure toward decomposition of reactive oxygen species (ROS) reduces the death of strictly anaerobic bacteria by fivefold in the presence of 21% O2, and enables the cytoprotected bacteria to continuously produce acetate from CO2 fixation under oxidative stress. The high definition of the MOF–bacteria interface involving direct bonding between phosphate units on the cell surface and zirconium clusters on MOF monolayer, provides for enhancement of life throughout reproduction. The dynamic nature of the MOF wrapping allows for cell elongation and separation, including spontaneous covering of the newly grown cell surface. Finally, the open-metal sites on the zirconium clusters lead to 600 times more efficient ROS decomposition compared with zirconia nanoparticles.},
doi = {10.1073/pnas.1808829115},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
number = 42,
volume = 115,
place = {United States},
year = {Mon Oct 01 00:00:00 EDT 2018},
month = {Mon Oct 01 00:00:00 EDT 2018}
}
Free Publicly Available Full Text
Publisher's Version of Record
Other availability
Search WorldCat to find libraries that may hold this journal
Cited by: 111 works
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Improvement of Biological Organisms Using Functional Material Shells
journal, February 2016
- Liu, Zhaoming; Xu, Xurong; Tang, Ruikang
- Advanced Functional Materials, Vol. 26, Issue 12
Characterization of Zirconium Phosphate/Polycation Thin Films Grown by Sequential Adsorption Reactions
journal, June 1997
- Kim, Hyuk-Nyun; Keller, Steven W.; Mallouk, Thomas E.
- Chemistry of Materials, Vol. 9, Issue 6
Effects of γ-Radiation on Ice 1
journal, July 1956
- Ghormley, J. A.; Stewart, A. C.
- Journal of the American Chemical Society, Vol. 78, Issue 13
Metal-Organic Framework Coatings as Cytoprotective Exoskeletons for Living Cells
journal, July 2016
- Liang, Kang; Richardson, Joseph J.; Cui, Jiwei
- Advanced Materials, Vol. 28, Issue 36
Kinetics, Mechanism, and Activation Energy of H 2 O 2 Decomposition on the Surface of ZrO 2
journal, June 2010
- Lousada, Cláudio M.; Jonsson, Mats
- The Journal of Physical Chemistry C, Vol. 114, Issue 25
Nanowire–Bacteria Hybrids for Unassisted Solar Carbon Dioxide Fixation to Value-Added Chemicals
journal, April 2015
- Liu, Chong; Gallagher, Joseph J.; Sakimoto, Kelsey K.
- Nano Letters, Vol. 15, Issue 5
Electrostatic Layer-by-Layer Nanoassembly on Biological Microtemplates: Platelets
journal, May 2002
- Ai, Hua; Fang, Ming; Jones, Steven A.
- Biomacromolecules, Vol. 3, Issue 3
Self-photosensitization of nonphotosynthetic bacteria for solar-to-chemical production
journal, December 2015
- Sakimoto, K. K.; Wong, A. B.; Yang, P.
- Science, Vol. 351, Issue 6268
Chemical and Fuel Production by Anaerobic Bacteria
journal, October 1980
- Zeikus, J. G.
- Annual Review of Microbiology, Vol. 34, Issue 1
Biomimetic Encapsulation of Individual Cells with Silica
journal, November 2009
- Yang, Sung Ho; Lee, Kyung-Bok; Kong, Bokyung
- Angewandte Chemie International Edition, Vol. 48, Issue 48
Wall Teichoic Acids of Gram-Positive Bacteria
journal, September 2013
- Brown, Stephanie; Santa Maria, John P.; Walker, Suzanne
- Annual Review of Microbiology, Vol. 67, Issue 1
Teichoic Acids and Membrane Function in Bacteria
journal, February 1970
- Heptinstall, S.; Archibald, A. R.; Baddiley, J.
- Nature, Vol. 225, Issue 5232
Hybrid bioinorganic approach to solar-to-chemical conversion
journal, August 2015
- Nichols, Eva M.; Gallagher, Joseph J.; Liu, Chong
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 37
Self-Supporting Metal-Organic Layers as Single-Site Solid Catalysts
journal, March 2016
- Cao, Lingyun; Lin, Zekai; Peng, Fei
- Angewandte Chemie International Edition, Vol. 55, Issue 16
Mechanism of H 2 O 2 Decomposition on Transition Metal Oxide Surfaces
journal, April 2012
- Lousada, Cláudio M.; Johansson, Adam Johannes; Brinck, Tore
- The Journal of Physical Chemistry C, Vol. 116, Issue 17
Constructing vesicle-based artificial cells with embedded living cells as organelle-like modules
journal, March 2018
- Elani, Yuval; Trantidou, Tatiana; Wylie, Douglas
- Scientific Reports, Vol. 8, Issue 1
Organelle-Specific Triggered Release of Immunostimulatory Oligonucleotides from Intrinsically Coordinated DNA–Metal–Organic Frameworks with Soluble Exoskeleton
journal, October 2017
- Wang, Zejun; Fu, Yao; Kang, Zhengzhong
- Journal of the American Chemical Society, Vol. 139, Issue 44
Water splitting–biosynthetic system with CO 2 reduction efficiencies exceeding photosynthesis
journal, June 2016
- Liu, Chong; Colón, Brendan C.; Ziesack, Marika
- Science, Vol. 352, Issue 6290
Efficient solar-to-fuels production from a hybrid microbial–water-splitting catalyst system
journal, February 2015
- Torella, Joseph P.; Gagliardi, Christopher J.; Chen, Janice S.
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 8
Chemical diversity in a metal–organic framework revealed by fluorescence lifetime imaging
journal, April 2018
- Schrimpf, Waldemar; Jiang, Juncong; Ji, Zhe
- Nature Communications, Vol. 9, Issue 1
Formation of H 2 O 2 in TiO 2 Photocatalysis of Oxygenated and Deoxygenated Aqueous Systems: A Probe for Photocatalytically Produced Hydroxyl Radicals
journal, May 2014
- Diesen, Veronica; Jonsson, Mats
- The Journal of Physical Chemistry C, Vol. 118, Issue 19
Cysteine–Cystine Photoregeneration for Oxygenic Photosynthesis of Acetic Acid from CO 2 by a Tandem Inorganic–Biological Hybrid System
journal, August 2016
- Sakimoto, Kelsey K.; Zhang, Stephanie J.; Yang, Peidong
- Nano Letters, Vol. 16, Issue 9
An Enzyme-Coated Metal-Organic Framework Shell for Synthetically Adaptive Cell Survival
journal, June 2017
- Liang, Kang; Richardson, Joseph J.; Doonan, Christian J.
- Angewandte Chemie International Edition, Vol. 56, Issue 29
Nanocoating of Single Cells: From Maintenance of Cell Viability to Manipulation of Cellular Activities
journal, January 2014
- Park, Ji Hun; Yang, Sung Ho; Lee, Juno
- Advanced Materials, Vol. 26, Issue 13
Biomimetic Encapsulation of Individual Cells with Silica
journal, November 2009
- Yang, Sung Ho; Lee, Kyung-Bok; Kong, Bokyung
- Angewandte Chemie, Vol. 121, Issue 48
An Enzyme-Coated Metal-Organic Framework Shell for Synthetically Adaptive Cell Survival
journal, June 2017
- Liang, Kang; Richardson, Joseph J.; Doonan, Christian J.
- Angewandte Chemie, Vol. 129, Issue 29
Self-Supporting Metal-Organic Layers as Single-Site Solid Catalysts
journal, March 2016
- Cao, Lingyun; Lin, Zekai; Peng, Fei
- Angewandte Chemie, Vol. 128, Issue 16
Nanocoating of Single Cells: From Maintenance of Cell Viability to Manipulation of Cellular Activities
journal, January 2014
- Park, Ji Hun; Yang, Sung Ho; Lee, Juno
- Advanced Materials, Vol. 26, Issue 13
Metal-Organic Framework Coatings as Cytoprotective Exoskeletons for Living Cells
journal, July 2016
- Liang, Kang; Richardson, Joseph J.; Cui, Jiwei
- Advanced Materials, Vol. 28, Issue 36
Self-Supporting Metal-Organic Layers as Single-Site Solid Catalysts
journal, March 2016
- Cao, Lingyun; Lin, Zekai; Peng, Fei
- Angewandte Chemie International Edition, Vol. 55, Issue 16
An Enzyme-Coated Metal-Organic Framework Shell for Synthetically Adaptive Cell Survival
journal, June 2017
- Liang, Kang; Richardson, Joseph J.; Doonan, Christian J.
- Angewandte Chemie International Edition, Vol. 56, Issue 29
Nanowire–Bacteria Hybrids for Unassisted Solar Carbon Dioxide Fixation to Value-Added Chemicals
journal, April 2015
- Liu, Chong; Gallagher, Joseph J.; Sakimoto, Kelsey K.
- Nano Letters, Vol. 15, Issue 5
Electrostatic Layer-by-Layer Nanoassembly on Biological Microtemplates: Platelets
journal, May 2002
- Ai, Hua; Fang, Ming; Jones, Steven A.
- Biomacromolecules, Vol. 3, Issue 3
Effects of γ-Radiation on Ice 1
journal, July 1956
- Ghormley, J. A.; Stewart, A. C.
- Journal of the American Chemical Society, Vol. 78, Issue 13
Organelle-Specific Triggered Release of Immunostimulatory Oligonucleotides from Intrinsically Coordinated DNA–Metal–Organic Frameworks with Soluble Exoskeleton
journal, October 2017
- Wang, Zejun; Fu, Yao; Kang, Zhengzhong
- Journal of the American Chemical Society, Vol. 139, Issue 44
Teichoic Acids and Membrane Function in Bacteria
journal, February 1970
- Heptinstall, S.; Archibald, A. R.; Baddiley, J.
- Nature, Vol. 225, Issue 5232
Chemical diversity in a metal–organic framework revealed by fluorescence lifetime imaging
journal, April 2018
- Schrimpf, Waldemar; Jiang, Juncong; Ji, Zhe
- Nature Communications, Vol. 9, Issue 1
Constructing vesicle-based artificial cells with embedded living cells as organelle-like modules
journal, March 2018
- Elani, Yuval; Trantidou, Tatiana; Wylie, Douglas
- Scientific Reports, Vol. 8, Issue 1
Efficient solar-to-fuels production from a hybrid microbial–water-splitting catalyst system
journal, February 2015
- Torella, Joseph P.; Gagliardi, Christopher J.; Chen, Janice S.
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 8
Hybrid bioinorganic approach to solar-to-chemical conversion
journal, August 2015
- Nichols, Eva M.; Gallagher, Joseph J.; Liu, Chong
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 37
Tolerance and Metabolic Response of Acetogenic Bacteria toward Oxygen
journal, February 2002
- Karnholz, A.; Kusel, K.; Go ner, A.
- Applied and Environmental Microbiology, Vol. 68, Issue 2
Hydrogen-Dependent Oxygen Reduction by Homoacetogenic Bacteria Isolated from Termite Guts
journal, February 2003
- Boga, H. I.; Brune, A.
- Applied and Environmental Microbiology, Vol. 69, Issue 2
Cytochrome bd Oxidase, Oxidative Stress, and Dioxygen Tolerance of the Strictly Anaerobic Bacterium Moorella thermoacetica
journal, March 2005
- Das, A.; Silaghi-Dumitrescu, R.; Ljungdahl, L. G.
- Journal of Bacteriology, Vol. 187, Issue 6
Wall Teichoic Acids of Gram-Positive Bacteria
journal, September 2013
- Brown, Stephanie; Santa Maria, John P.; Walker, Suzanne
- Annual Review of Microbiology, Vol. 67, Issue 1
Chemical and Fuel Production by Anaerobic Bacteria
journal, October 1980
- Zeikus, J. G.
- Annual Review of Microbiology, Vol. 34, Issue 1
Works referencing / citing this record:
Biocatalytic Metal‐Organic Framework‐Based Artificial Cells
journal, August 2019
- Liu, Jian; Guo, Ziyi; Liang, Kang
- Advanced Functional Materials, Vol. 29, Issue 45
SupraCells: Living Mammalian Cells Protected within Functional Modular Nanoparticle‐Based Exoskeletons
journal, April 2019
- Zhu, Wei; Guo, Jimin; Amini, Shahrouz
- Advanced Materials, Vol. 31, Issue 25
Nanoarchitectonics of Biofunctionalized Metal–Organic Frameworks with Biological Macromolecules and Living Cells
journal, May 2019
- Dutta, Saikat; Kim, Jeonghun; Hsieh, Pin‐Hsun
- Small Methods, Vol. 3, Issue 11
Photoluminescent organisms: how to make fungi glow through biointegration with lanthanide metal-organic frameworks
journal, May 2019
- Rosário, Jeferson; da Luz, Leonis L.; Geris, Regina
- Scientific Reports, Vol. 9, Issue 1
Solar-driven carbon dioxide fixation using photosynthetic semiconductor bio-hybrids
journal, January 2019
- Cestellos-Blanco, Stefano; Zhang, Hao; Yang, Peidong
- Faraday Discussions, Vol. 215
Effective loading of cisplatin into a nanoscale UiO-66 metal–organic framework with preformed defects
journal, January 2019
- Lin, Shi-Xin; Pan, Wei-Lun; Niu, Ru-Jie
- Dalton Transactions, Vol. 48, Issue 16
Cisplatin delivery, anticancer and antibacterial properties of Fe/SBA-16/ZIF-8 nanocomposite
journal, January 2019
- Balasamy, Rabindran Jermy; Ravinayagam, Vijaya; Alomari, Munther
- RSC Advances, Vol. 9, Issue 72
Photoluminescent organisms: how to make fungi glow through biointegration with lanthanide metal-organic frameworks
journal, May 2019
- Rosário, Jeferson; da Luz, Leonis L.; Geris, Regina
- Scientific Reports, Vol. 9, Issue 1
Nanobiohybrids: Materials approaches for bioaugmentation
journal, March 2020
- Guo, Ziyi; Richardson, Joseph J.; Kong, Biao
- Science Advances, Vol. 6, Issue 12
Metal-Organic Framework Nanoparticle-Based Biomineralization: A New Strategy toward Cancer Treatment
journal, January 2019
- Chu, Chengchao; Su, Min; Zhu, Jing
- Theranostics, Vol. 9, Issue 11