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Title: Allele surfing promotes microbial adaptation from standing variation

Abstract

The coupling of ecology and evolution during range expansions enables mutations to establish at expanding range margins and reach high frequencies. This phenomenon, called allele surfing, is thought to have caused revolutions in the gene pool of many species, most evidently in microbial communities. It has remained unclear, however, under which conditions allele surfing promotes or hinders adaptation. Here in this paper, using microbial experiments and simulations, we show that, starting with standing adaptive variation, range expansions generate a larger increase in mean fitness than spatially uniform population expansions. The adaptation gain results from ‘soft’ selective sweeps emerging from surfing beneficial mutations. The rate of these surfing events is shown to sensitively depend on the strength of genetic drift, which varies among strains and environmental conditions. More generally, allele surfing promotes the rate of adaptation per biomass produced, which could help developing biofilms and other resource-limited populations to cope with environmental challenges.

Authors:
 [1];  [2];  [3];  [1];  [3];  [1]
  1. Univ. of California, Berkeley, CA (United States)
  2. Max Planck Inst. for Dynamics and Self-Organization, Gottingen (Germany)
  3. Univ. of Edinburgh, Scotland (United Kingdom)
Publication Date:
Research Org.:
Univ. of California, Berkeley, CA (United States)
Sponsoring Org.:
National Science Foundation (NSF); National Institutes of Health (NIH); USDOE Office of Science (SC)
OSTI Identifier:
1418631
Alternate Identifier(s):
OSTI ID: 1401683
Grant/Contract Number:  
AC02-05CH11231
Resource Type:
Accepted Manuscript
Journal Name:
Ecology Letters
Additional Journal Information:
Journal Volume: 19; Journal Issue: 8; Journal ID: ISSN 1461-023X
Publisher:
Wiley
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; Biological invasions; dynamics of adaptation; eco-evolutionary feedback; gene surfing; genetic drift; range expansions

Citation Formats

Gralka, Matti, Stiewe, Fabian, Farrell, Fred, Mobius, Wolfram, Waclaw, Bartlomiej, and Hallatschek, Oskar. Allele surfing promotes microbial adaptation from standing variation. United States: N. p., 2016. Web. doi:10.1111/ele.12625.
Gralka, Matti, Stiewe, Fabian, Farrell, Fred, Mobius, Wolfram, Waclaw, Bartlomiej, & Hallatschek, Oskar. Allele surfing promotes microbial adaptation from standing variation. United States. doi:10.1111/ele.12625.
Gralka, Matti, Stiewe, Fabian, Farrell, Fred, Mobius, Wolfram, Waclaw, Bartlomiej, and Hallatschek, Oskar. Thu . "Allele surfing promotes microbial adaptation from standing variation". United States. doi:10.1111/ele.12625. https://www.osti.gov/servlets/purl/1418631.
@article{osti_1418631,
title = {Allele surfing promotes microbial adaptation from standing variation},
author = {Gralka, Matti and Stiewe, Fabian and Farrell, Fred and Mobius, Wolfram and Waclaw, Bartlomiej and Hallatschek, Oskar},
abstractNote = {The coupling of ecology and evolution during range expansions enables mutations to establish at expanding range margins and reach high frequencies. This phenomenon, called allele surfing, is thought to have caused revolutions in the gene pool of many species, most evidently in microbial communities. It has remained unclear, however, under which conditions allele surfing promotes or hinders adaptation. Here in this paper, using microbial experiments and simulations, we show that, starting with standing adaptive variation, range expansions generate a larger increase in mean fitness than spatially uniform population expansions. The adaptation gain results from ‘soft’ selective sweeps emerging from surfing beneficial mutations. The rate of these surfing events is shown to sensitively depend on the strength of genetic drift, which varies among strains and environmental conditions. More generally, allele surfing promotes the rate of adaptation per biomass produced, which could help developing biofilms and other resource-limited populations to cope with environmental challenges.},
doi = {10.1111/ele.12625},
journal = {Ecology Letters},
number = 8,
volume = 19,
place = {United States},
year = {2016},
month = {6}
}

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Cited by: 24 works
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Works referenced in this record:

Capillary flow as the cause of ring stains from dried liquid drops
journal, October 1997

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