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Title: Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging

Authors:
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  1. Gordon Center for Medical Imaging & Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital & Department of Radiology, Harvard Medical School, Boston MA 02114 USA
  2. Pfizer Worldwide Research and Development, Groton Laboratories, Eastern Point Road Groton CT 06340 USA
  3. Pfizer Worldwide Research and Development, 610 Main Street Cambridge MA 02139 USA
  4. Departments of Neurology & Psychiatry, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street Boston MA 02114 USA
  5. Stanley Center for Psychiatric Research, Broad Institute, 415 Main Street Cambridge MA o2142 USA
  6. Stanley Center for Psychiatric Research, Broad Institute, 415 Main Street Cambridge MA o2142 USA, Departments of Neurology & Psychiatry, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street Boston MA 02114 USA
Publication Date:
Grant/Contract Number:
AC02-06CH11357
Type:
Publisher's Accepted Manuscript
Journal Name:
Angewandte Chemie
Additional Journal Information:
Journal Volume: 128; Journal Issue: 33; Related Information: CHORUS Timestamp: 2017-10-20 17:06:26; Journal ID: ISSN 0044-8249
Publisher:
Wiley Blackwell (John Wiley & Sons)
Sponsoring Org:
USDOE
Country of Publication:
Germany
Language:
English
OSTI Identifier:
1401450