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Title: Genomic analysis of three Bifidobacterium species isolated from the calf gastrointestinal tract

Abstract

Ruminant animals contribute significantly to the global value of agriculture and rely on a complex microbial community for efficient digestion. However, little is known of how this microbial-host relationship develops and is maintained. To begin to address this, we have determined the ability of three Bifidobacterium species isolated from the faeces of newborn calves to grow on carbohydrates typical of a newborn ruminant diet. Genome sequences have been determined for these bacteria with analysis of the genomes providing insights into the host association and identification of several genes that may mediate interactions with the ruminant gastrointestinal tract. The present study provides a starting point from which we can define the role of potential beneficial microbes in the nutrition of young ruminants and begin to influence the interactions between the microbiota and the host. The differences observed in genomic content hint at niche partitioning among the bifidobacterial species analysed and the different strategies they employ to successfully adapt to this habitat.

Authors:
 [1];  [1];  [1];  [1];  [1];  [1];  [1];  [2];  [2];  [1]
  1. Grasslands Research Centre, Palmerston North (New Zealand)
  2. USDOE Joint Genome Institute (JGI), Walnut Creek, CA (United States)
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
OSTI Identifier:
1379531
Grant/Contract Number:  
AC02-05CH11231
Resource Type:
Accepted Manuscript
Journal Name:
Scientific Reports
Additional Journal Information:
Journal Volume: 6; Journal Issue: 1; Journal ID: ISSN 2045-2322
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; bacterial genomics; bacteriology

Citation Formats

Kelly, William J., Cookson, Adrian L., Altermann, Eric, Lambie, Suzanne C., Perry, Rechelle, Teh, Koon Hoong, Otter, Don E., Shapiro, Nicole, Woyke, Tanja, and Leahy, Sinead C. Genomic analysis of three Bifidobacterium species isolated from the calf gastrointestinal tract. United States: N. p., 2016. Web. doi:10.1038/srep30768.
Kelly, William J., Cookson, Adrian L., Altermann, Eric, Lambie, Suzanne C., Perry, Rechelle, Teh, Koon Hoong, Otter, Don E., Shapiro, Nicole, Woyke, Tanja, & Leahy, Sinead C. Genomic analysis of three Bifidobacterium species isolated from the calf gastrointestinal tract. United States. doi:10.1038/srep30768.
Kelly, William J., Cookson, Adrian L., Altermann, Eric, Lambie, Suzanne C., Perry, Rechelle, Teh, Koon Hoong, Otter, Don E., Shapiro, Nicole, Woyke, Tanja, and Leahy, Sinead C. Fri . "Genomic analysis of three Bifidobacterium species isolated from the calf gastrointestinal tract". United States. doi:10.1038/srep30768. https://www.osti.gov/servlets/purl/1379531.
@article{osti_1379531,
title = {Genomic analysis of three Bifidobacterium species isolated from the calf gastrointestinal tract},
author = {Kelly, William J. and Cookson, Adrian L. and Altermann, Eric and Lambie, Suzanne C. and Perry, Rechelle and Teh, Koon Hoong and Otter, Don E. and Shapiro, Nicole and Woyke, Tanja and Leahy, Sinead C.},
abstractNote = {Ruminant animals contribute significantly to the global value of agriculture and rely on a complex microbial community for efficient digestion. However, little is known of how this microbial-host relationship develops and is maintained. To begin to address this, we have determined the ability of three Bifidobacterium species isolated from the faeces of newborn calves to grow on carbohydrates typical of a newborn ruminant diet. Genome sequences have been determined for these bacteria with analysis of the genomes providing insights into the host association and identification of several genes that may mediate interactions with the ruminant gastrointestinal tract. The present study provides a starting point from which we can define the role of potential beneficial microbes in the nutrition of young ruminants and begin to influence the interactions between the microbiota and the host. The differences observed in genomic content hint at niche partitioning among the bifidobacterial species analysed and the different strategies they employ to successfully adapt to this habitat.},
doi = {10.1038/srep30768},
journal = {Scientific Reports},
number = 1,
volume = 6,
place = {United States},
year = {2016},
month = {7}
}

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    Works referencing / citing this record:

    Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum
    journal, September 2017

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