DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

Journal Article · · Science

Not Available

Sponsoring Organization:
USDOE
OSTI ID:
1355834
Journal Information:
Science, Journal Name: Science Journal Issue: 6274 Vol. 351; ISSN 0036-8075
Publisher:
American Association for the Advancement of Science (AAAS)Copyright Statement
Country of Publication:
United States
Language:
English

References (51)

What determines the van der Waals coefficient ? in the LIE (linear interaction energy) method to estimate binding free energies using molecular dynamics simulations? journal February 1999
Comparative Protein Structure Modeling Using MODELLER journal September 2014
Activating CD94:NKG2C and inhibitory CD94:NKG2A receptors are expressed by distinct subsets of committed CD8+ TCR ?? lymphocytes journal December 2004
Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines : Immunity to infection journal February 2015
Improved side-chain torsion potentials for the Amber ff99SB protein force field journal January 2010
Sub-angstrom modeling of complexes between flexible peptides and globular proteins journal January 2010
The HLA-A2 Restricted T Cell Epitope HCV Core35–44 Stabilizes HLA-E Expression and Inhibits Cytolysis Mediated by Natural Killer Cells journal February 2005
Confronting Complexity: Real-World Immunodominance in Antiviral CD8+ T Cell Responses journal October 2006
Basic and translational applications of engineered MHC class I proteins journal October 2010
Subtle Changes in Peptide Conformation Profoundly Affect Recognition of the Non-Classical MHC Class I Molecule HLA-E by the CD94–NKG2 Natural Killer Cell Receptors journal April 2008
The role of mhc polymorphism in anti-microbial resistance journal April 2004
The other Janus face of Qa-1 and HLA-E: diverse peptide repertoires in times of stress journal November 2010
Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2 journal January 2013
Subangstrom Accuracy in pHLA-I Modeling by Rosetta FlexPepDock Refinement Protocol journal July 2014
P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation journal December 2007
Establishment of a quantitative ELISA capable of determining peptide - MHC class I interaction journal April 2002
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C journal February 1998
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine journal May 2011
Immune clearance of highly pathogenic SIV infection journal September 2013
Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge journal February 2009
Major histocompatibility complex genotyping with massively parallel pyrosequencing journal October 2009
Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection journal May 2002
Impact of MHC class I diversity on immune control of immunodeficiency virus replication journal August 2008
Towards a systems understanding of MHC class I and MHC class II antigen presentation journal November 2011
Viral modulation of NK cell immunity journal January 2005
Molecular dynamics with coupling to an external bath journal October 1984
A smooth particle mesh Ewald method journal November 1995
Efficient replication of rhesus cytomegalovirus variants in multiple rhesus and human cell types journal December 2008
HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A journal April 1998
HLA-E Allelic Variants: CORRELATING DIFFERENTIAL EXPRESSION, PEPTIDE AFFINITIES, CRYSTAL STRUCTURES, AND THERMAL STABILITIES journal October 2002
GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit journal February 2013
Epock: rapid analysis of protein pocket dynamics journal December 2014
Rapid modification of bacterial artificial chromosomes by ET- recombination journal March 1999
Rosetta FlexPepDock web server—high resolution modeling of peptide–protein interactions journal May 2011
Simple and highly efficient BAC recombineering using galK selection journal February 2005
A highly sensitive selection method for directed evolution of homing endonucleases journal October 2005
A new method for predicting binding affinity in computer-aided drug design journal January 1994
WebLogo: A Sequence Logo Generator journal May 2004
The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity journal November 2008
Clinical and immunological significance of HLA-E in stem cell transplantation and cancer: HLA-E in transplantation and cancer journal November 2014
Cytomegalovirus Vectors Violate CD8+ T Cell Epitope Recognition Paradigms journal May 2013
The Cytoplasmic Domain of Rhesus Cytomegalovirus Rh178 Interrupts Translation of Major Histocompatibility Class I Leader Peptide-Containing Proteins prior to Translocation journal June 2011
New Paradigms for HIV/AIDS Vaccine Development journal February 2012
The Emerging Role of HLA-E-Restricted CD8 + T Lymphocytes in the Adaptive Immune Response to Pathogens and Tumors journal January 2010
Composition Profiler: a tool for discovery and visualization of amino acid composition differences journal January 2007
Regulation and trafficking of the HLA-E molecules during monocyte-macrophage differentiation journal August 2015
The Mycobacterium tuberculosis Phagosome Is a HLA-I Processing Competent Organelle journal April 2009
Human Cytomegalovirus UL40 Signal Peptide Regulates Cell Surface Expression of the NK Cell Ligands HLA-E and gpUL18 journal February 2012
Cutting Edge: The Human Cytomegalovirus UL40 Gene Product Contains a Ligand for HLA-E and Prevents NK Cell-Mediated Lysis journal May 2000
Analysis of HLA-E Peptide-Binding Specificity and Contact Residues in Bound Peptide Required for Recognition by CD94/NKG2 journal July 2003
Gag-Specific CD8 + T Lymphocytes Recognize Infected Cells before AIDS-Virus Integration and Viral Protein Expression journal February 2007