Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts
Abstract
The effect of global climate change on infectious disease remains hotly debated because multiple extrinsic and intrinsic drivers interact to influence transmission dynamics in nonlinear ways. The dominant drivers of widespread pathogens, like West Nile virus, can be challenging to identify due to regional variability in vector and host ecology, with past studies producing disparate findings. Here, we used analyses at national and state scales to examine a suite of climatic and intrinsic drivers of continental-scale West Nile virus epidemics, including an empirically derived mechanistic relationship between temperature and transmission potential that accounts for spatial variability in vectors. We found that drought was the primary climatic driver of increased West Nile virus epidemics, rather than within-season or winter temperatures, or precipitation independently. Local-scale data from one region suggested drought increased epidemics via changes in mosquito infection prevalence rather than mosquito abundance. In addition, human acquired immunity following regional epidemics limited subsequent transmission in many states. We show that over the next 30 years, increased drought severity from climate change could triple West Nile virus cases, but only in regions with low human immunity. Lastly, these results illustrate how changes in drought severity can alter the transmission dynamics of vector-borne diseases.
- Authors:
-
[1];
[6]
- Univ. of California, Santa Cruz, CA (United States); National Center for Atmospheric Research, Boulder, CO (United States)
- Northwestern Univ., Evanston, IL (United States); Stanford Univ., Stanford, CA (United States)
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- New York State Dept. of Health, Slingerlands, NY (United States); SUNY, Albany, NY (United States)
- Stanford Univ., Stanford, CA (United States)
- Univ. of California, Santa Cruz, CA (United States)
- Publication Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States). Oak Ridge Leadership Computing Facility (OLCF)
- Sponsoring Org.:
- USDOE Office of Science (SC)
- OSTI Identifier:
- 1344995
- Grant/Contract Number:
- AC05-00OR22725
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Proceedings of the Royal Society B: Biological Sciences
- Additional Journal Information:
- Journal Volume: 284; Journal Issue: 1848; Journal ID: ISSN 0962-8452
- Publisher:
- The Royal Society Publishing
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 54 ENVIRONMENTAL SCIENCES; vector-borne disease; nonlinear temperature–disease relationship; Culex; disease ecology; global warming
Citation Formats
Paull, Sara H., Horton, Daniel E., Ashfaq, Moetasim, Rastogi, Deeksha, Kramer, Laura D., Diffenbaugh, Noah S., and Kilpatrick, A. Marm. Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts. United States: N. p., 2017.
Web. doi:10.1098/rspb.2016.2078.
Paull, Sara H., Horton, Daniel E., Ashfaq, Moetasim, Rastogi, Deeksha, Kramer, Laura D., Diffenbaugh, Noah S., & Kilpatrick, A. Marm. Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts. United States. https://doi.org/10.1098/rspb.2016.2078
Paull, Sara H., Horton, Daniel E., Ashfaq, Moetasim, Rastogi, Deeksha, Kramer, Laura D., Diffenbaugh, Noah S., and Kilpatrick, A. Marm. Wed .
"Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts". United States. https://doi.org/10.1098/rspb.2016.2078. https://www.osti.gov/servlets/purl/1344995.
@article{osti_1344995,
title = {Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts},
author = {Paull, Sara H. and Horton, Daniel E. and Ashfaq, Moetasim and Rastogi, Deeksha and Kramer, Laura D. and Diffenbaugh, Noah S. and Kilpatrick, A. Marm},
abstractNote = {The effect of global climate change on infectious disease remains hotly debated because multiple extrinsic and intrinsic drivers interact to influence transmission dynamics in nonlinear ways. The dominant drivers of widespread pathogens, like West Nile virus, can be challenging to identify due to regional variability in vector and host ecology, with past studies producing disparate findings. Here, we used analyses at national and state scales to examine a suite of climatic and intrinsic drivers of continental-scale West Nile virus epidemics, including an empirically derived mechanistic relationship between temperature and transmission potential that accounts for spatial variability in vectors. We found that drought was the primary climatic driver of increased West Nile virus epidemics, rather than within-season or winter temperatures, or precipitation independently. Local-scale data from one region suggested drought increased epidemics via changes in mosquito infection prevalence rather than mosquito abundance. In addition, human acquired immunity following regional epidemics limited subsequent transmission in many states. We show that over the next 30 years, increased drought severity from climate change could triple West Nile virus cases, but only in regions with low human immunity. Lastly, these results illustrate how changes in drought severity can alter the transmission dynamics of vector-borne diseases.},
doi = {10.1098/rspb.2016.2078},
journal = {Proceedings of the Royal Society B: Biological Sciences},
number = 1848,
volume = 284,
place = {United States},
year = {Wed Feb 08 00:00:00 EST 2017},
month = {Wed Feb 08 00:00:00 EST 2017}
}
Free Publicly Available Full Text
Publisher's Version of Record
Other availability
Search WorldCat to find libraries that may hold this journal
Cited by: 88 works
Citation information provided by
Web of Science
Web of Science
Figures / Tables:
Figure 1: Mechanisms influencing WNV transmission. (a) Variables (blue/white) that influence human WNND cases (red/dark grey) either positively (green/whitearrows) or negatively (black arrows), either directly, or via effects on mosquito populations (purple/light grey). Note that it is the product of mosquito abundance and prevalence that determine risk to humans. Themore »
All figures and tables
(4 total)
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Effects of Temperature on the Transmission of West Nile Virus by Culex tarsalis (Diptera: Culicidae)
journal, March 2006
- Reisen, William K.; Fang, Ying; Martinez, Vincent M.
- Journal of Medical Entomology, Vol. 43, Issue 2
Altitudinal Changes in Malaria Incidence in Highlands of Ethiopia and Colombia
journal, March 2014
- Siraj, A. S.; Santos-Vega, M.; Bouma, M. J.
- Science, Vol. 343, Issue 6175
Supplementary material from "Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts"
other, February 2017
- Paull, Sara H.; Horton, Daniel E.; Ashfaq, Moetasim
- Figshare-Supplementary information for journal article at DOI: 10.1098/rspb.2016.2078, 1 docx file (5.38 MB)
Hydrologic Conditions Describe West Nile Virus Risk in Colorado
journal, February 2010
- Shaman, Jeffrey; Day, Jonathan F.; Komar, Nicholas
- International Journal of Environmental Research and Public Health, Vol. 7, Issue 2
The challenge of emerging and re-emerging infectious diseases
journal, July 2004
- Morens, David M.; Folkers, Gregory K.; Fauci, Anthony S.
- Nature, Vol. 430, Issue 6996
Ecological and immunological determinants of dengue epidemics
journal, July 2006
- Wearing, H. J.; Rohani, P.
- Proceedings of the National Academy of Sciences, Vol. 103, Issue 31
West Nile virus emergence and large-scale declines of North American bird populations
journal, May 2007
- LaDeau, Shannon L.; Kilpatrick, A. Marm; Marra, Peter P.
- Nature, Vol. 447, Issue 7145
Drought-Induced Amplification and Epidemic Transmission of West Nile Virus in Southern Florida
journal, March 2005
- Shaman, Jeffrey; Day, Jonathan F.; Stieglitz, Marc
- Journal of Medical Entomology, Vol. 42, Issue 2
Climate change projections of West Nile virus infections in Europe: implications for blood safety practices
journal, March 2016
- Semenza, Jan C.; Tran, Annelise; Espinosa, Laura
- Environmental Health, Vol. 15, Issue S1
Predicting Human West Nile Virus Infections With Mosquito Surveillance Data
journal, July 2013
- Kilpatrick, A. Marm; Pape, W. John
- American Journal of Epidemiology, Vol. 178, Issue 5
West Nile Virus Infection Among Health-Fair Participants, Wyoming 2003: Assessment of Symptoms and Risk Factors
journal, September 2005
- Murphy, Tracy D.; Grandpre, Joe; Novick, Sandra L.
- Vector-Borne and Zoonotic Diseases, Vol. 5, Issue 3
A Contribution to the Mathematical Theory of Epidemics
journal, August 1927
- Kermack, W. O.; McKendrick, A. G.
- Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, Vol. 115, Issue 772
Weather Factors Influencing the Population Dynamics of Culex pipiens (Diptera: Culicidae) in the Po Plain Valley, Italy (1997-2011)
journal, April 2014
- Carrieri, Marco; Fariselli, Piero; Maccagnani, Bettina
- Environmental Entomology, Vol. 43, Issue 2
Opposite Patterns of Synchrony in Sympatric Disease Metapopulations
journal, October 1999
- Rohani, P.
- Science, Vol. 286, Issue 5441
Mosquito Surveillance Revealed Lagged Effects of Mosquito Abundance on Mosquito-Borne Disease Transmission: A Retrospective Study in Zhejiang, China
journal, November 2014
- Guo, Song; Ling, Feng; Hou, Juan
- PLoS ONE, Vol. 9, Issue 11
The Effect of Temperature on Life History Traits of Culex Mosquitoes
journal, January 2014
- Ciota, Alexander T.; Matacchiero, Amy C.; Kilpatrick, A. Marm
- Journal of Medical Entomology, Vol. 51, Issue 1
Impact of regional climate change on human health
journal, November 2005
- Patz, Jonathan A.; Campbell-Lendrum, Diarmid; Holloway, Tracey
- Nature, Vol. 438, Issue 7066
National and Regional Associations Between Human West Nile Virus Incidence and Demographic, Landscape, and Land Use Conditions in the Coterminous United States
journal, August 2012
- DeGroote, John P.; Sugumaran, Ramanathan
- Vector-Borne and Zoonotic Diseases, Vol. 12, Issue 8
Ecology of Mosquitoes and St. Louis Encephalitis Virus in the Los Angeles Basin of California, 1987–1990
journal, July 1992
- Reisen, W. K.; Milby, M. M.; Presser, S. B.
- Journal of Medical Entomology, Vol. 29, Issue 4
Effect of Temperature on Culex tarsalis (Diptera: Culicidae) from the Coachella and San Joaquin Valleys of California
journal, September 1995
- Reisen, William K.
- Journal of Medical Entomology, Vol. 32, Issue 5
Infectious Disease in a Warming World: How Weather Influenced West Nile Virus in the United States (2001–2005)
journal, July 2009
- Soverow, Jonathan E.; Wellenius, Gregory A.; Fisman, David N.
- Environmental Health Perspectives, Vol. 117, Issue 7
Risk factors for human infection with West Nile Virus in Connecticut: a multi-year analysis
journal, January 2009
- Liu, Ann; Lee, Vivian; Galusha, Deron
- International Journal of Health Geographics, Vol. 8, Issue 1
Predicting Culex pipiens/restuans population dynamics by interval lagged weather data
journal, May 2013
- Lebl, Karin; Brugger, Katharina; Rubel, Franz
- Parasites & Vectors, Vol. 6, Issue 1
Drought-induced mosquito outbreaks in wetlands: Drought-induced mosquito outbreaks in wetlands
journal, September 2003
- Chase, Jonathan M.; Knight, Tiffany M.
- Ecology Letters, Vol. 6, Issue 11
Mosquito, Bird and Human Surveillance of West Nile and Usutu Viruses in Emilia-Romagna Region (Italy) in 2010
journal, May 2012
- Calzolari, Mattia; Gaibani, Paolo; Bellini, Romeo
- PLoS ONE, Vol. 7, Issue 5
Climate Change and Infectious Diseases: From Evidence to a Predictive Framework
journal, August 2013
- Altizer, S.; Ostfeld, R. S.; Johnson, P. T. J.
- Science, Vol. 341, Issue 6145
Anthropogenic warming has increased drought risk in California
journal, March 2015
- Diffenbaugh, Noah S.; Swain, Daniel L.; Touma, Danielle
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 13
Evidence for Co-evolution of West Nile Virus and House Sparrows in North America
journal, October 2014
- Duggal, Nisha K.; Bosco-Lauth, Angela; Bowen, Richard A.
- PLoS Neglected Tropical Diseases, Vol. 8, Issue 10
West Nile Virus: Review of the Literature
journal, July 2013
- Petersen, Lyle R.; Brault, Aaron C.; Nasci, Roger S.
- JAMA, Vol. 310, Issue 3
Optimal temperature for malaria transmission is dramatically lower than previously predicted
journal, October 2012
- Mordecai, Erin A.; Paaijmans, Krijn P.; Johnson, Leah R.
- Ecology Letters, Vol. 16, Issue 1
Regional and seasonal response of a West Nile virus vector to climate change
journal, September 2013
- Morin, C. W.; Comrie, A. C.
- Proceedings of the National Academy of Sciences, Vol. 110, Issue 39
Superspreading and the effect of individual variation on disease emergence
journal, November 2005
- Lloyd-Smith, J. O.; Schreiber, S. J.; Kopp, P. E.
- Nature, Vol. 438, Issue 7066
Meteorological and Hydrological Influences on the Spatial and Temporal Prevalence of West Nile Virus in <I>Culex</I> Mosquitoes, Suffolk County, New York
journal, July 2011
- Shaman, Jeffrey; Harding, Kerri; Campbell, Scott R.
- Journal of Medical Entomology, Vol. 48, Issue 4
Using climate impacts indicators to evaluate climate model ensembles: temperature suitability of premium winegrape cultivation in the United States
journal, May 2012
- Diffenbaugh, Noah S.; Scherer, Martin
- Climate Dynamics, Vol. 40, Issue 3-4
Driving forces for changes in geographical distribution of Ixodes ricinus ticks in Europe
journal, January 2013
- Medlock, Jolyon M.; Hansford, Kayleigh M.; Bormane, Antra
- Parasites & Vectors, Vol. 6, Issue 1
Globalization, Land Use, and the Invasion of West Nile Virus
journal, October 2011
- Kilpatrick, A. M.
- Science, Vol. 334, Issue 6054
Response of air stagnation frequency to anthropogenically enhanced radiative forcing
journal, November 2012
- Horton, Daniel E.; Diffenbaugh, Noah S.
- Environmental Research Letters, Vol. 7, Issue 4
Drought under global warming: a review: Drought under global warming
journal, October 2010
- Dai, Aiguo
- Wiley Interdisciplinary Reviews: Climate Change, Vol. 2, Issue 1
Refractory periods and climate forcing in cholera dynamics
journal, August 2005
- Koelle, Katia; Rodó, Xavier; Pascual, Mercedes
- Nature, Vol. 436, Issue 7051
The Role of Hydrogeography and Climate in the Landscape Epidemiology of West Nile Virus in New York State from 2000 to 2010
journal, February 2012
- Walsh, Michael G.
- PLoS ONE, Vol. 7, Issue 2
Inter-Annual Associations Between Precipitation and Human Incidence of West Nile Virus in the United States
journal, September 2007
- Landesman, William J.; Allan, Brian F.; Langerhans, R. Brian
- Vector-Borne and Zoonotic Diseases, Vol. 7, Issue 3
The Global Spread of Malaria in a Future, Warmer World
journal, September 2000
- Rogers, David J.; Randolph, Sarah E.
- Science, Vol. 289, Issue 5485
Flushing Effect of Rain on Container-Inhabiting Mosquitoes Aedes aegypti and Culex pipiens (Diptera: Culicidae)
journal, January 2008
- Koenraadt, C. J. M.; Harrington, L. C.
- Journal of Medical Entomology, Vol. 45, Issue 1
Host stress hormones alter vector feeding preferences, success, and productivity
journal, August 2016
- Gervasi, Stephanie S.; Burkett-Cadena, Nathan; Burgan, Sarah C.
- Proceedings of the Royal Society B: Biological Sciences, Vol. 283, Issue 1836
Local impact of temperature and precipitation on West Nile virus infection in Culex species mosquitoes in northeast Illinois, USA
journal, January 2010
- Ruiz, Marilyn O.; Chaves, Luis F.; Hamer, Gabriel L.
- Parasites & Vectors, Vol. 3, Issue 1
Drought-Induced Amplification and Epidemic Transmission of West Nile Virus in Southern Florida
journal, March 2005
- Shaman, Jeffrey; Day, Jonathan F.; Stieglitz, Marc
- Journal of Medical Entomology, Vol. 42, Issue 2
Rapid Amplification of West Nile Virus: The Role of Hatch-Year Birds
journal, February 2008
- Hamer, Gabriel L.; Walker, Edward D.; Brawn, Jeffrey D.
- Vector-Borne and Zoonotic Diseases, Vol. 8, Issue 1
Mixed effects models and extensions in ecology with R
book, January 2009
- Zuur, Alain F.; Ieno, Elena N.; Walker, Neil
- Statistics for Biology and Health
Monitoring EU Emerging Infectious Disease Risk Due to Climate Change
journal, April 2012
- Lindgren, E.; Andersson, Y.; Suk, J. E.
- Science, Vol. 336, Issue 6080
Heterogeneities in the transmission of infectious agents: Implications for the design of control programs
journal, January 1997
- Woolhouse, M. E. J.; Dye, C.; Etard, J. - F.
- Proceedings of the National Academy of Sciences, Vol. 94, Issue 1
A continental risk assessment of West Nile virus under climate change
journal, February 2014
- Harrigan, Ryan J.; Thomassen, Henri A.; Buermann, Wolfgang
- Global Change Biology, Vol. 20, Issue 8
Meteorological Conditions Associated with Increased Incidence of West Nile Virus Disease in the United States, 2004–2012
journal, May 2015
- Nasci, Roger S.; Delorey, Mark J.; Eisen, Rebecca J.
- The American Journal of Tropical Medicine and Hygiene, Vol. 92, Issue 5
Data from: Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts
dataset, January 2017
- Paull, S. H.; Horton, D. E.; Ashfaq, M.
- Dryad, 1.085 Kb
The challenge to keep global warming below 2 °C
journal, December 2012
- Peters, Glen P.; Andrew, Robbie M.; Boden, Tom
- Nature Climate Change, Vol. 3, Issue 1
Modelling the effect of temperature on the seasonal population dynamics of temperate mosquitoes
journal, July 2016
- Ewing, D. A.; Cobbold, C. A.; Purse, B. V.
- Journal of Theoretical Biology, Vol. 400
Unpredictable and Difficult to Control — The Adolescence of West Nile Virus
journal, October 2012
- Petersen, Lyle R.; Fischer, Marc
- New England Journal of Medicine, Vol. 367, Issue 14
Temperature, Viral Genetics, and the Transmission of West Nile Virus by Culex pipiens Mosquitoes
journal, June 2008
- Kilpatrick, A. Marm; Meola, Mark A.; Moudy, Robin M.
- PLoS Pathogens, Vol. 4, Issue 6
Emergence of novel Leptospira serovars: a need for adjusting vaccination policies for dogs?
journal, September 2012
- Arent, Z. J.; Andrews, S.; Adamama-Moraitou, K.
- Epidemiology and Infection, Vol. 141, Issue 6
Effects of drought on avian community structure: DROUGHT AND AVIAN COMMUNITY STRUCTURE
journal, December 2009
- Albright, Thomas P.; Pidgeon, Anna M.; Rittenhouse, Chadwick D.
- Global Change Biology, Vol. 16, Issue 8
The 2012 West Nile Encephalitis Epidemic in Dallas, Texas
journal, July 2013
- Chung, Wendy M.; Buseman, Christen M.; Joyner, Sibeso N.
- JAMA, Vol. 310, Issue 3
Effect of Trapping Methods, Weather, and Landscape on Estimates of the Culex Vector Mosquito Abundance
journal, January 2016
- Karki, Surendra; Hamer, Gabriel L.; Anderson, Tavis K.
- Environmental Health Insights, Vol. 10
High-resolution ensemble projections of near-term regional climate over the continental United States: CLIMATE PROJECTIONS OVER THE U.S.
journal, September 2016
- Ashfaq, Moetasim; Rastogi, Deeksha; Mei, Rui
- Journal of Geophysical Research: Atmospheres, Vol. 121, Issue 17
Effective control of SARS-CoV-2 transmission in Wanzhou, China
journal, November 2020
- Shi, Qiuling; Hu, Yaoyue; Peng, Bin
- Nature Medicine, Vol. 27, Issue 1
Data from: Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts
dataset, January 2017
- Paull, S. H.; Horton, D. E.; Ashfaq, M.
- Dryad, 1.085 Kb
Works referencing / citing this record:
Bibliometric analysis of peer-reviewed literature on climate change and human health with an emphasis on infectious diseases
journal, May 2020
- Sweileh, Waleed M.
- Globalization and Health, Vol. 16, Issue 1
Thermal biology of mosquito‐borne disease
journal, July 2019
- Mordecai, Erin A.; Caldwell, Jamie M.; Grossman, Marissa K.
- Ecology Letters, Vol. 22, Issue 10
The drivers of West Nile virus human illness: fine scale dynamic effects of weather, mosquito infection, social, and biological conditions
posted_content, December 2019
- Karki, Surendra; Brown, William M.; Uelmen, John
Key Factors Influencing the Incidence of West Nile Virus in Burleigh County, North Dakota
journal, September 2018
- Mori, Hiroko; Wu, Joshua; Ibaraki, Motomu
- International Journal of Environmental Research and Public Health, Vol. 15, Issue 9
Impact of West Nile Virus on Bird Populations: Limited Lasting Effects, Evidence for Recovery, and Gaps in Our Understanding of Impacts on Ecosystems
journal, September 2019
- Kilpatrick, A. Marm; Wheeler, Sarah S.
- Journal of Medical Entomology, Vol. 56, Issue 6
Dehydration prompts increased activity and blood feeding by mosquitoes
journal, May 2018
- Hagan, Richard W.; Didion, Elise M.; Rosselot, Andrew E.
- Scientific Reports, Vol. 8, Issue 1
The knowns and unknowns of West Nile virus in Europe: what did we learn from the 2018 outbreak?
journal, January 2020
- Camp, Jeremy V.; Nowotny, Norbert
- Expert Review of Anti-infective Therapy, Vol. 18, Issue 2
The Impact of Global Environmental Changes on Infectious Disease Emergence with a Focus on Risks for Brazil
journal, January 2017
- Nava, Alessandra; Shimabukuro, Juliana Suieko; Chmura, Aleksei A.
- ILAR Journal, Vol. 58, Issue 3
Seasonal temperatures and hydrological conditions improve the prediction of West Nile virus infection rates in Culex mosquitoes and human case counts in New York and Connecticut
journal, June 2019
- Keyel, Alexander C.; Elison Timm, Oliver; Backenson, P. Bryon
- PLOS ONE, Vol. 14, Issue 6
Forecasting Zoonotic Infectious Disease Response to Climate Change: Mosquito Vectors and a Changing Environment
journal, May 2019
- Bartlow, Andrew W.; Manore, Carrie; Xu, Chonggang
- Veterinary Sciences, Vol. 6, Issue 2
Biological Adaptations Associated with Dehydration in Mosquitoes
journal, October 2019
- Holmes, Christopher J.; Benoit, Joshua B.
- Insects, Vol. 10, Issue 11
On the Fly: Interactions Between Birds, Mosquitoes, and Environment That Have Molded West Nile Virus Genomic Structure Over Two Decades
journal, September 2019
- Duggal, Nisha K.; Langwig, Kate E.; Ebel, Gregory D.
- Journal of Medical Entomology, Vol. 56, Issue 6
A quantitative comparison of West Nile virus incidence from 2013 to 2018 in Emilia-Romagna, Italy
journal, January 2020
- Marini, Giovanni; Calzolari, Mattia; Angelini, Paola
- PLOS Neglected Tropical Diseases, Vol. 14, Issue 1
Introduction, Spread, and Establishment of West Nile Virus in the Americas
journal, September 2019
- Kramer, Laura D.; Ciota, Alexander T.; Kilpatrick, A. Marm
- Journal of Medical Entomology, Vol. 56, Issue 6
Models and Surveillance Systems to Detect and Predict West Nile Virus Outbreaks
journal, September 2019
- Barker, Christopher M.
- Journal of Medical Entomology, Vol. 56, Issue 6
Parsing the effects of demography, climate and management on recurrent brucellosis outbreaks in elk
journal, December 2019
- Cotterill, Gavin G.; Cross, Paul C.; Merkle, Jerod A.
- Journal of Applied Ecology, Vol. 57, Issue 2
Estimating the Health‐Related Costs of 10 Climate‐Sensitive U.S. Events During 2012
journal, September 2019
- Limaye, Vijay S.; Max, Wendy; Constible, Juanita
- GeoHealth, Vol. 3, Issue 9
Drought severity and all-cause mortality rates among adults in the United States: 1968–2014
journal, May 2020
- Lynch, Katie M.; Lyles, Robert H.; Waller, Lance A.
- Environmental Health, Vol. 19, Issue 1
Modeling the average population of La Crosse vectors in Knox County, Tennessee
journal, January 2019
- Ghatak, Maitraya; Urcuyo, Javier; Wise, Patrick
- Letters in Biomathematics, Vol. 6, Issue 1
Long-term surveillance defines spatial and temporal patterns implicating Culex tarsalis as the primary vector of West Nile virus
journal, April 2019
- Dunphy, Brendan M.; Kovach, Kristofer B.; Gehrke, Ella J.
- Scientific Reports, Vol. 9, Issue 1
Crossover Dynamics of Culex (Diptera: Culicidae) Vector Populations Determine WNV Transmission Intensity
journal, July 2019
- Tokarz, Ryan E.; Smith, Ryan C.
- Journal of Medical Entomology
Temperature explains broad patterns of Ross River virus transmission across Australia
posted_content, April 2018
- Shocket, Marta S.; Ryan, Sadie J.; Mordecai, Erin A.
Linking the vectorial capacity of multiple vectors to observed patterns of West Nile virus transmission
journal, January 2019
- McMillan, Joseph R.; Blakney, Rebekah A.; Mead, Daniel G.
- Journal of Applied Ecology, Vol. 56, Issue 4
Bovine tuberculosis disturbs parasite functional trait composition in African buffalo
journal, July 2019
- Beechler, Brianna R.; Boersma, Kate S.; Buss, Peter E.
- Proceedings of the National Academy of Sciences, Vol. 116, Issue 29
Effects of climate change on vector-borne diseases: an updated focus on West Nile virus in humans
journal, April 2019
- Paz, Shlomit
- Emerging Topics in Life Sciences, Vol. 3, Issue 2
Trends and gaps in forecasting plant virus disease risk
journal, November 2019
- McLeish, Michael J.; Fraile, Aurora; García‐Arenal, Fernando
- Annals of Applied Biology, Vol. 176, Issue 2
Scientists’ warning to humanity: microorganisms and climate change
journal, June 2019
- Cavicchioli, Ricardo; Ripple, William J.; Timmis, Kenneth N.
- Nature Reviews Microbiology, Vol. 17, Issue 9
Temperature explains broad patterns of Ross River virus transmission
journal, August 2018
- Shocket, Marta Strecker; Ryan, Sadie J.; Mordecai, Erin A.
- eLife, Vol. 7
Data from: Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts
dataset, January 2017
- Paull, S. H.; Horton, D. E.; Ashfaq, M.
- Dryad, 1.085 Kb
Modeling the Average Population of La Crosse Vectors in Knox County, Tennessee
journal, January 2019
- Lenhart, Suzanne; Urcuyo, Javier; Wise, Patrick
- Letters in Biomathematics, Vol. 6, Issue 1
Scientists’ warning to humanity: microorganisms and climate change
text, January 2019
- Cavicchioli, Ricardo; Ripple, William J.; Timmis, Kenneth N.
- ETH Zurich
Data from: Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts
dataset, January 2017
- Paull, S. H.; Horton, D. E.; Ashfaq, M.
- Dryad, 1.085 Kb
Estimating the Health‐Related Costs of 10 Climate‐Sensitive U.S. Events During 2012
journal, September 2019
- Limaye, Vijay S.; Max, Wendy; Constible, Juanita
- GeoHealth, Vol. 3, Issue 9
Dehydration prompts increased activity and blood feeding by mosquitoes
journal, May 2018
- Hagan, Richard W.; Didion, Elise M.; Rosselot, Andrew E.
- Scientific Reports, Vol. 8, Issue 1
Seasonal temperatures and hydrological conditions improve the prediction of West Nile virus infection rates in Culex mosquitoes and human case counts in New York and Connecticut
journal, June 2019
- Keyel, Alexander C.; Elison Timm, Oliver; Backenson, P. Bryon
- PLOS ONE, Vol. 14, Issue 6
Twenty years of West Nile virus spread and evolution in the Americas visualized by Nextstrain
journal, October 2019
- Hadfield, James; Brito, Anderson F.; Swetnam, Daniele M.
- PLOS Pathogens, Vol. 15, Issue 10
Key Factors Influencing the Incidence of West Nile Virus in Burleigh County, North Dakota
journal, September 2018
- Mori, Hiroko; Wu, Joshua; Ibaraki, Motomu
- International Journal of Environmental Research and Public Health, Vol. 15, Issue 9
Temperature explains broad patterns of Ross River virus transmission
journal, August 2018
- Shocket, Marta Strecker; Ryan, Sadie J.; Mordecai, Erin A.
- eLife, Vol. 7
Figures / Tables found in this record:
Figures/Tables have been extracted from DOE-funded journal article accepted manuscripts.