The iQID Camera: An Ionizing-Radiation Quantum Imaging Detector
Abstract
We have developed and tested a novel, ionizing-radiation Quantum Imaging Detector (iQID). This scintillation-based detector was originally developed as a high-resolution gamma-ray imager, called BazookaSPECT, for use in single-photon emission computed tomography (SPECT). Recently, we have investigated the detectors response and imaging potential with other forms of ionizing radiation including alpha, neutron, beta, and fission fragment particles. The detector’s response to a broad range of ionizing radiation has prompted its new title. The principle operation of the iQID camera involves coupling a scintillator to an image intensifier. The scintillation light generated particle interactions is optically amplified by the intensifier and then re-imaged onto a CCD/CMOS camera sensor. The intensifier provides sufficient optical gain that practically any CCD/CMOS camera can be used to image ionizing radiation. Individual particles are identified and their spatial position (to sub-pixel accuracy) and energy are estimated on an event-by-event basis in real time using image analysis algorithms on high-performance graphics processing hardware. Distinguishing features of the iQID camera include portability, large active areas, high sensitivity, and high spatial resolution (tens of microns). Although modest, iQID has energy resolution that is sufficient to discrimate between particles. Additionally, spatial features of individual events can be used for particlemore »
- Authors:
-
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Univ. of Arizona, Tucson, AZ (United States). College of Optical Sciences
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
- Univ. of Arizona, Tucson, AZ (United States). Center for Gamma-Ray Imaging; Univ. of Arizona, Tucson, AZ (United States). College of Optical Sciences
- Publication Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1221503
- Report Number(s):
- PNNL-SA-100301
Journal ID: ISSN 0168-9002
- Grant/Contract Number:
- AC05-76RL01830; P41EB002035
- Resource Type:
- Accepted Manuscript
- Journal Name:
- Nuclear Instruments and Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment
- Additional Journal Information:
- Journal Volume: 767; Journal ID: ISSN 0168-9002
- Publisher:
- Elsevier
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; Charged particle imaging detectors; Ionizing radiation; BazookaSPECT; Digital autoradiography
Citation Formats
Miller, Brian W., Gregory, Stephanie J., Fuller, Erin S., Barrett, Harrison H., Barber, Bradford H., and Furenlid, Lars R. The iQID Camera: An Ionizing-Radiation Quantum Imaging Detector. United States: N. p., 2014.
Web. doi:10.1016/j.nima.2014.05.070.
Miller, Brian W., Gregory, Stephanie J., Fuller, Erin S., Barrett, Harrison H., Barber, Bradford H., & Furenlid, Lars R. The iQID Camera: An Ionizing-Radiation Quantum Imaging Detector. United States. https://doi.org/10.1016/j.nima.2014.05.070
Miller, Brian W., Gregory, Stephanie J., Fuller, Erin S., Barrett, Harrison H., Barber, Bradford H., and Furenlid, Lars R. Wed .
"The iQID Camera: An Ionizing-Radiation Quantum Imaging Detector". United States. https://doi.org/10.1016/j.nima.2014.05.070. https://www.osti.gov/servlets/purl/1221503.
@article{osti_1221503,
title = {The iQID Camera: An Ionizing-Radiation Quantum Imaging Detector},
author = {Miller, Brian W. and Gregory, Stephanie J. and Fuller, Erin S. and Barrett, Harrison H. and Barber, Bradford H. and Furenlid, Lars R.},
abstractNote = {We have developed and tested a novel, ionizing-radiation Quantum Imaging Detector (iQID). This scintillation-based detector was originally developed as a high-resolution gamma-ray imager, called BazookaSPECT, for use in single-photon emission computed tomography (SPECT). Recently, we have investigated the detectors response and imaging potential with other forms of ionizing radiation including alpha, neutron, beta, and fission fragment particles. The detector’s response to a broad range of ionizing radiation has prompted its new title. The principle operation of the iQID camera involves coupling a scintillator to an image intensifier. The scintillation light generated particle interactions is optically amplified by the intensifier and then re-imaged onto a CCD/CMOS camera sensor. The intensifier provides sufficient optical gain that practically any CCD/CMOS camera can be used to image ionizing radiation. Individual particles are identified and their spatial position (to sub-pixel accuracy) and energy are estimated on an event-by-event basis in real time using image analysis algorithms on high-performance graphics processing hardware. Distinguishing features of the iQID camera include portability, large active areas, high sensitivity, and high spatial resolution (tens of microns). Although modest, iQID has energy resolution that is sufficient to discrimate between particles. Additionally, spatial features of individual events can be used for particle discrimination. An important iQID imaging application that has recently been developed is single-particle, real-time digital autoradiography. In conclusion, we present the latest results and discuss potential applications.},
doi = {10.1016/j.nima.2014.05.070},
journal = {Nuclear Instruments and Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment},
number = ,
volume = 767,
place = {United States},
year = {Wed Jun 11 00:00:00 EDT 2014},
month = {Wed Jun 11 00:00:00 EDT 2014}
}
Free Publicly Available Full Text
Publisher's Version of Record
Other availability
Search WorldCat to find libraries that may hold this journal
Cited by: 54 works
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Recent advances in BazookaSPECT: Real-time data processing and the development of a gamma-ray microscope
journal, June 2008
- Miller, Brian W.; Barrett, Harrison H.; Furenlid, Lars R.
- Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 591, Issue 1
A prototype detector for a novel high-resolution PET system: BazookaPET
conference, October 2012
- Park, Ryeojin; Miller, Brian W.; Jha, Abhinav K.
- 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference (2012 NSS/MIC), 2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)
Structured CsI(Tl) scintillators for X-ray imaging applications
journal, June 1998
- Nagarkar, V. V.; Gupta, T. K.; Miller, S. R.
- IEEE Transactions on Nuclear Science, Vol. 45, Issue 3
Large-Area Crystalline Microcolumnar LaBr$_{3}$:Ce for High-Resolution Gamma Ray Imaging
journal, February 2013
- Bhandari, Harish B.; Gelfandbein, Vladimir; Miller, Stuart R.
- IEEE Transactions on Nuclear Science, Vol. 60, Issue 1
Maximum-Likelihood Methods for Processing Signals From Gamma-Ray Detectors
journal, June 2009
- Barrett, Harrison H.; Hunter, William C. J.; Miller, Brian William
- IEEE Transactions on Nuclear Science, Vol. 56, Issue 3
Progress of BazookaSPECT
conference, September 2009
- Miller, Brian W.; Barber, H. Bradford; Furenlid, Lars R.
- SPIE Optical Engineering + Applications, SPIE Proceedings
Connected component labeling on a 2D grid using CUDA
journal, April 2011
- Kalentev, Oleksandr; Rai, Abha; Kemnitz, Stefan
- Journal of Parallel and Distributed Computing, Vol. 71, Issue 4
2003: A centennial of spinthariscope and scintillation counting
journal, August 2004
- Kolar, Z. I.; den Hollander, W.
- Applied Radiation and Isotopes, Vol. 61, Issue 2-3
Coincident Time-of-Flight Measurements of the Velocities of Fission Fragments
journal, August 1963
- Whetstone, Stanley L.
- Physical Review, Vol. 131, Issue 3
Inorganic scintillators for thermal neutron detection
journal, August 2004
- van Eijk, Carel W. E.
- Radiation Measurements, Vol. 38, Issue 4-6
Isotopic conversion in gadolinium-exposure neutron imaging
journal, June 1974
- Harms, A. A.; McCormack, G.
- Nuclear Instruments and Methods, Vol. 118, Issue 2
A new sensor for thermal neutron imaging
journal, August 2005
- Shestakova, I.; Tipnis, S. V.; Gaysinskiy, V.
- IEEE Transactions on Nuclear Science, Vol. 52, Issue 4
Photon-counting gamma camera based on columnar CsI(Tl) optically coupled to a back-illuminated CCD
conference, March 2007
- Miller, Brian W.; Barber, H. Bradford; Barrett, Harrison H.
- Medical Imaging, SPIE Proceedings
Californium-252 as a Neutron Source for BNCT
book, January 2012
- Miller, Albert
- Neutron Capture Therapy
Works referencing / citing this record:
Evaluation of 209 At as a theranostic isotope for 209 At-radiopharmaceutical development using high-energy SPECT
journal, February 2018
- Crawford, J. R.; Robertson, A. K. H.; Yang, H.
- Physics in Medicine & Biology, Vol. 63, Issue 4
Internal microdosimetry of alpha-emitting radionuclides
journal, December 2019
- Hofmann, Werner; Li, Wei Bo; Friedland, Werner
- Radiation and Environmental Biophysics, Vol. 59, Issue 1
Modular low-light microscope for imaging cellular bioluminescence and radioluminescence
journal, April 2017
- Kim, Tae Jin; Türkcan, Silvan; Pratx, Guillem
- Nature Protocols, Vol. 12, Issue 5
Singular value decomposition for photon-processing nuclear imaging systems and applications for reconstruction and computing null functions
journal, September 2015
- Jha, Abhinav K.; Barrett, Harrison H.; Frey, Eric C.
- Physics in Medicine and Biology, Vol. 60, Issue 18
Development of Targeted Alpha Particle Therapy for Solid Tumors
journal, November 2019
- Tafreshi, Narges K.; Doligalski, Michael L.; Tichacek, Christopher J.
- Molecules, Vol. 24, Issue 23
Possibility analysis of bremsstrahlung x-ray imaging of C-14 radionuclide using a LaGPS radiation imaging system
journal, April 2019
- Yamamoto, Seiichi; Nakanishi, Kouhei; Furukawa, Takako
- Biomedical Physics & Engineering Express, Vol. 5, Issue 3
Physiological random processes in precision cancer therapy
journal, June 2018
- Henscheid, Nick; Clarkson, Eric; Myers, Kyle J.
- PLOS ONE, Vol. 13, Issue 6
Charged-particle emission tomography
journal, May 2017
- Ding, Yijun; Caucci, Luca; Barrett, Harrison H.
- Medical Physics, Vol. 44, Issue 6
Internal microdosimetry of alpha-emitting radionuclides
journal, December 2019
- Hofmann, Werner; Li, Wei Bo; Friedland, Werner
- Radiation and Environmental Biophysics, Vol. 59, Issue 1
Combination Radioimmunotherapy Approaches and Quantification of Immuno-PET
journal, January 2016
- Kim, Jin Su
- Nuclear Medicine and Molecular Imaging, Vol. 50, Issue 2
Null functions in three-dimensional imaging of alpha and beta particles
journal, November 2017
- Ding, Yijun; Caucci, Luca; Barrett, Harrison H.
- Scientific Reports, Vol. 7, Issue 1
Ultrahigh resolution radiation imaging system using an optical fiber structure scintillator plate
journal, February 2018
- Yamamoto, Seiichi; Kamada, Kei; Yoshikawa, Akira
- Scientific Reports, Vol. 8, Issue 1
Development of Targeted Alpha Particle Therapy for Solid Tumors
journal, November 2019
- Tafreshi, Narges K.; Doligalski, Michael L.; Tichacek, Christopher J.
- Molecules, Vol. 24, Issue 23