Abstract
The purpose of this study was to evaluate chest CTA protocol using retrospective ECG-gating and triphasic IV contrast regimen for comprehensive evaluation of patients with acute non-specific chest pain. ECG-triggered dose modulation was used with a 64-MDCT scanner in 56 non-critically ill patients with acute nonspecific chest pain using triphasic IV regimen: 50 ml contrast followed by 50 ml 60% contrast/saline and 30 ml normal saline. Lungs, aorta, pulmonary and coronary arteries were graded on a 5-point scale (5, best). Aorta and pulmonary artery attenuation was measured and three coronary artery groups were evaluated. Comparison with invasive coronary angiography was obtained in nine patients on a per segment (16 total) basis. Dosimetry values were obtained. Studies were satisfactory in all patients (score >3). Aorta and pulmonary artery attenuation was >200 HU in 90.5%. Lung or pleura, non-cardiac vascular and coronary arteries disease were detected in 20, 11 and 16 patients, respectively. Median coronary angiography (grade 5) was significantly higher than acceptable for diagnosis grade 4 (p < 0.001). Per segment, weighted kappa statistic was 0.79 indicating substantial agreement with catheter angiography (p<0.001). Average DLP was 1,490 {+-} 412 mGy-cm. Gated 64-MDCT angiography with triphasic IV contrast is a robust multipurpose
More>>
Litmanovitch, Diana;
Zamboni, Giulia A;
Lin, Pei-Jan P;
Clouse, Melvin E;
Raptopoulos, Vassilios;
[1]
Harvard Medical School, Department of Radiology, Boston, MA (United States)];
Hauser, Thomas H;
[2]
Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Cardiology, Boston, MA (United States)]
- Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Radiology, Boston, MA (United States)
- Harvard Medical School, Department of Radiology, Boston, MA (United States)
Citation Formats
Litmanovitch, Diana, Zamboni, Giulia A, Lin, Pei-Jan P, Clouse, Melvin E, Raptopoulos, Vassilios, Harvard Medical School, Department of Radiology, Boston, MA (United States)], Hauser, Thomas H, and Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Cardiology, Boston, MA (United States)].
ECG-gated chest CT angiography with 64-MDCT and tri-phasic IV contrast administration regimen in patients with acute non-specific chest pain.
Germany: N. p.,
2008.
Web.
doi:10.1007/S00330-007-0739-2.
Litmanovitch, Diana, Zamboni, Giulia A, Lin, Pei-Jan P, Clouse, Melvin E, Raptopoulos, Vassilios, Harvard Medical School, Department of Radiology, Boston, MA (United States)], Hauser, Thomas H, & Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Cardiology, Boston, MA (United States)].
ECG-gated chest CT angiography with 64-MDCT and tri-phasic IV contrast administration regimen in patients with acute non-specific chest pain.
Germany.
https://doi.org/10.1007/S00330-007-0739-2
Litmanovitch, Diana, Zamboni, Giulia A, Lin, Pei-Jan P, Clouse, Melvin E, Raptopoulos, Vassilios, Harvard Medical School, Department of Radiology, Boston, MA (United States)], Hauser, Thomas H, and Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Cardiology, Boston, MA (United States)].
2008.
"ECG-gated chest CT angiography with 64-MDCT and tri-phasic IV contrast administration regimen in patients with acute non-specific chest pain."
Germany.
https://doi.org/10.1007/S00330-007-0739-2.
@misc{etde_21001566,
title = {ECG-gated chest CT angiography with 64-MDCT and tri-phasic IV contrast administration regimen in patients with acute non-specific chest pain}
author = {Litmanovitch, Diana, Zamboni, Giulia A, Lin, Pei-Jan P, Clouse, Melvin E, Raptopoulos, Vassilios, Harvard Medical School, Department of Radiology, Boston, MA (United States)], Hauser, Thomas H, and Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Cardiology, Boston, MA (United States)]}
abstractNote = {The purpose of this study was to evaluate chest CTA protocol using retrospective ECG-gating and triphasic IV contrast regimen for comprehensive evaluation of patients with acute non-specific chest pain. ECG-triggered dose modulation was used with a 64-MDCT scanner in 56 non-critically ill patients with acute nonspecific chest pain using triphasic IV regimen: 50 ml contrast followed by 50 ml 60% contrast/saline and 30 ml normal saline. Lungs, aorta, pulmonary and coronary arteries were graded on a 5-point scale (5, best). Aorta and pulmonary artery attenuation was measured and three coronary artery groups were evaluated. Comparison with invasive coronary angiography was obtained in nine patients on a per segment (16 total) basis. Dosimetry values were obtained. Studies were satisfactory in all patients (score >3). Aorta and pulmonary artery attenuation was >200 HU in 90.5%. Lung or pleura, non-cardiac vascular and coronary arteries disease were detected in 20, 11 and 16 patients, respectively. Median coronary angiography (grade 5) was significantly higher than acceptable for diagnosis grade 4 (p < 0.001). Per segment, weighted kappa statistic was 0.79 indicating substantial agreement with catheter angiography (p<0.001). Average DLP was 1,490 {+-} 412 mGy-cm. Gated 64-MDCT angiography with triphasic IV contrast is a robust multipurpose technique for patients with acute non-specific chest pain. (orig.)}
doi = {10.1007/S00330-007-0739-2}
journal = []
issue = {2}
volume = {18}
place = {Germany}
year = {2008}
month = {Feb}
}
title = {ECG-gated chest CT angiography with 64-MDCT and tri-phasic IV contrast administration regimen in patients with acute non-specific chest pain}
author = {Litmanovitch, Diana, Zamboni, Giulia A, Lin, Pei-Jan P, Clouse, Melvin E, Raptopoulos, Vassilios, Harvard Medical School, Department of Radiology, Boston, MA (United States)], Hauser, Thomas H, and Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Cardiology, Boston, MA (United States)]}
abstractNote = {The purpose of this study was to evaluate chest CTA protocol using retrospective ECG-gating and triphasic IV contrast regimen for comprehensive evaluation of patients with acute non-specific chest pain. ECG-triggered dose modulation was used with a 64-MDCT scanner in 56 non-critically ill patients with acute nonspecific chest pain using triphasic IV regimen: 50 ml contrast followed by 50 ml 60% contrast/saline and 30 ml normal saline. Lungs, aorta, pulmonary and coronary arteries were graded on a 5-point scale (5, best). Aorta and pulmonary artery attenuation was measured and three coronary artery groups were evaluated. Comparison with invasive coronary angiography was obtained in nine patients on a per segment (16 total) basis. Dosimetry values were obtained. Studies were satisfactory in all patients (score >3). Aorta and pulmonary artery attenuation was >200 HU in 90.5%. Lung or pleura, non-cardiac vascular and coronary arteries disease were detected in 20, 11 and 16 patients, respectively. Median coronary angiography (grade 5) was significantly higher than acceptable for diagnosis grade 4 (p < 0.001). Per segment, weighted kappa statistic was 0.79 indicating substantial agreement with catheter angiography (p<0.001). Average DLP was 1,490 {+-} 412 mGy-cm. Gated 64-MDCT angiography with triphasic IV contrast is a robust multipurpose technique for patients with acute non-specific chest pain. (orig.)}
doi = {10.1007/S00330-007-0739-2}
journal = []
issue = {2}
volume = {18}
place = {Germany}
year = {2008}
month = {Feb}
}