{
  "date" : "2008-02-15",
  "identifier_doecontract" : "",
  "subject" : "62 RADIOLOGY AND NUCLEAR MEDICINE; BIOMEDICAL RADIOGRAPHY; CHEST; COMPUTERIZED TOMOGRAPHY; PAIN",
  "description" : "The purpose of this study was to evaluate chest CTA protocol using retrospective ECG-gating and triphasic IV contrast regimen for comprehensive evaluation of patients with acute non-specific chest pain. ECG-triggered dose modulation was used with a 64-MDCT scanner in 56 non-critically ill patients with acute nonspecific chest pain using triphasic IV regimen: 50 ml contrast followed by 50 ml 60% contrast/saline and 30 ml normal saline. Lungs, aorta, pulmonary and coronary arteries were graded on a 5-point scale (5, best). Aorta and pulmonary artery attenuation was measured and three coronary artery groups were evaluated. Comparison with invasive coronary angiography was obtained in nine patients on a per segment (16 total) basis. Dosimetry values were obtained. Studies were satisfactory in all patients (score >3). Aorta and pulmonary artery attenuation was >200 HU in 90.5%. Lung or pleura, non-cardiac vascular and coronary arteries disease were detected in 20, 11 and 16 patients, respectively. Median coronary angiography (grade 5) was significantly higher than acceptable for diagnosis grade 4 (p < 0.001). Per segment, weighted kappa statistic was 0.79 indicating substantial agreement with catheter angiography (p<0.001). Average DLP was 1,490 {+-} 412 mGy-cm. Gated 64-MDCT angiography with triphasic IV contrast is a robust multipurpose technique for patients with acute non-specific chest pain. (orig.)",
  "language" : "English",
  "identifier_report" : "",
  "publisher_sponsor" : "",
  "publisher_country" : "Germany",
  "source" : "DEN",
  "purl" : "",
  "title" : "ECG-gated chest CT angiography with 64-MDCT and tri-phasic IV contrast administration regimen in patients with acute non-specific chest pain",
  "type" : "Journal Article",
  "subject_related" : "",
  "relation" : "Journal Name: European Radiology; Journal Volume: 18; Journal Issue: 2",
  "entry_date" : "2010-01-01",
  "subject_list" : [ "62 RADIOLOGY AND NUCLEAR MEDICINE", "BIOMEDICAL RADIOGRAPHY", "CHEST", "COMPUTERIZED TOMOGRAPHY", "PAIN" ],
  "publisher_availability" : "Available from: http://dx.doi.org/10.1007/s00330-007-0739-2",
  "rights" : "",
  "announced_date" : "2008-04-14",
  "type_qualifier" : "",
  "has_fulltext" : false,
  "coverage" : "",
  "identifier" : "",
  "journal_volume" : "18",
  "creator" : "Litmanovitch, Diana; Zamboni, Giulia A; Lin, Pei-Jan P; Clouse, Melvin E; Raptopoulos, Vassilios [Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Radiology, Boston, MA (United States)]; Harvard Medical School, Department of Radiology, Boston, MA (United States)]; Hauser, Thomas H [Harvard Medical School, Department of Radiology, Boston, MA (United States)]; Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Cardiology, Boston, MA (United States)]",
  "site_ownership_code" : "DEN",
  "osti_id" : "21001566",
  "journal_issue" : "2",
  "resource_type" : "JOUR",
  "format" : "Medium: X; Size: page(s) 308-317",
  "journal_name" : [ ],
  "contributing_organizations" : "",
  "citation_location" : "https://www.osti.gov/etdeweb/biblio/21001566",
  "publication_year" : 2008,
  "subject_list_commas" : "62 RADIOLOGY AND NUCLEAR MEDICINE, BIOMEDICAL RADIOGRAPHY, CHEST, COMPUTERIZED TOMOGRAPHY, PAIN",
  "publisher" : "",
  "identifier_other" : "Journal ID: ISSN 0938-7994; EURAE3; TRN: DE08F3581",
  "publisher_research" : "",
  "creators_list" : [ "Litmanovitch, Diana", "Zamboni, Giulia A", "Lin, Pei-Jan P", "Clouse, Melvin E", "Raptopoulos, Vassilios [Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Radiology, Boston, MA (United States)]", "Harvard Medical School, Department of Radiology, Boston, MA (United States)]", "Hauser, Thomas H [Harvard Medical School, Department of Radiology, Boston, MA (United States)]", "Beth Israel Deaconess Medical Center and Harvard Medical School, Department of Cardiology, Boston, MA (United States)]" ],
  "doi" : "https://doi.org/10.1007/S00330-007-0739-2"
}