Robust Accurate Non-Invasive Analyte Monitor
Abstract
An improved method and apparatus for determining noninvasively and in vivo one or more unknown values of a known characteristic, particularly the concentration of an analyte in human tissue. The method includes: (1) irradiating the tissue with infrared energy (400 nm-2400 nm) having at least several wavelengths in a given range of wavelengths so that there is differential absorption of at least some of the wavelengths by the tissue as a function of the wavelengths and the known characteristic, the differential absorption causeing intensity variations of the wavelengths incident from the tissue; (2) providing a first path through the tissue; (3) optimizing the first path for a first sub-region of the range of wavelengths to maximize the differential absorption by at least some of the wavelengths in the first sub-region; (4) providing a second path through the tissue; and (5) optimizing the second path for a second sub-region of the range, to maximize the differential absorption by at least some of the wavelengths in the second sub-region. In the preferred embodiment a third path through the tissue is provided for, which path is optimized for a third sub-region of the range. With this arrangement, spectral variations which are the resultmore »
- Inventors:
-
- 1603 Solano NE., Albuquerque, NM 87110
- Issue Date:
- OSTI Identifier:
- 879399
- Patent Number(s):
- 5830132
- Application Number:
- 08/794677
- Assignee:
- Robinson, Mark R. (1603 Solano NE., Albuquerque, NM 87110)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Robinson, Mark R. Robust Accurate Non-Invasive Analyte Monitor. United States: N. p., 1998.
Web.
Robinson, Mark R. Robust Accurate Non-Invasive Analyte Monitor. United States.
Robinson, Mark R. Tue .
"Robust Accurate Non-Invasive Analyte Monitor". United States. https://www.osti.gov/servlets/purl/879399.
@article{osti_879399,
title = {Robust Accurate Non-Invasive Analyte Monitor},
author = {Robinson, Mark R},
abstractNote = {An improved method and apparatus for determining noninvasively and in vivo one or more unknown values of a known characteristic, particularly the concentration of an analyte in human tissue. The method includes: (1) irradiating the tissue with infrared energy (400 nm-2400 nm) having at least several wavelengths in a given range of wavelengths so that there is differential absorption of at least some of the wavelengths by the tissue as a function of the wavelengths and the known characteristic, the differential absorption causeing intensity variations of the wavelengths incident from the tissue; (2) providing a first path through the tissue; (3) optimizing the first path for a first sub-region of the range of wavelengths to maximize the differential absorption by at least some of the wavelengths in the first sub-region; (4) providing a second path through the tissue; and (5) optimizing the second path for a second sub-region of the range, to maximize the differential absorption by at least some of the wavelengths in the second sub-region. In the preferred embodiment a third path through the tissue is provided for, which path is optimized for a third sub-region of the range. With this arrangement, spectral variations which are the result of tissue differences (e.g., melanin and temperature) can be reduced. At least one of the paths represents a partial transmission path through the tissue. This partial transmission path may pass through the nail of a finger once and, preferably, twice. Also included are apparatus for: (1) reducing the arterial pulsations within the tissue; and (2) maximizing the blood content i the tissue.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 03 00:00:00 EST 1998},
month = {Tue Nov 03 00:00:00 EST 1998}
}
Works referenced in this record:
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