Biomolecular detection device
Abstract
A device for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with controllable pore size distribution characteristics applied to at least one surface of the conducting electrode. The film is functionalized with probe molecules that chemically interact with the target biomolecules at the film surface, blocking indicator molecules present in solution from diffusing from the solution to the electrode, thereby changing the electrochemical response of the electrode.
- Inventors:
-
- Albuquerque, NM
- Issue Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 985186
- Patent Number(s):
- 7439055
- Application Number:
- 11/120,935
- Assignee:
- NNSASC
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Huo, Qisheng, and Liu, Jun. Biomolecular detection device. United States: N. p., 2008.
Web.
Huo, Qisheng, & Liu, Jun. Biomolecular detection device. United States.
Huo, Qisheng, and Liu, Jun. Tue .
"Biomolecular detection device". United States. https://www.osti.gov/servlets/purl/985186.
@article{osti_985186,
title = {Biomolecular detection device},
author = {Huo, Qisheng and Liu, Jun},
abstractNote = {A device for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with controllable pore size distribution characteristics applied to at least one surface of the conducting electrode. The film is functionalized with probe molecules that chemically interact with the target biomolecules at the film surface, blocking indicator molecules present in solution from diffusing from the solution to the electrode, thereby changing the electrochemical response of the electrode.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 21 00:00:00 EDT 2008},
month = {Tue Oct 21 00:00:00 EDT 2008}
}
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Works referenced in this record:
Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA
journal, July 2003
- Fan, C.; Plaxco, K. W.; Heeger, A. J.
- Proceedings of the National Academy of Sciences, Vol. 100, Issue 16
Electrochemical characterization of monolayers of a biotinylated polythiophene: towards the development of polymeric biosensors
journal, January 2000
- Kumpumbu-Kalemba, Lievin; Leclerc, Mario
- Chemical Communications, Issue 19
Capacitance Measurements of Antibody−Antigen Interactions in a Flow System
journal, September 1997
- Berggren, Christine; Johansson, Gillis
- Analytical Chemistry, Vol. 69, Issue 18
Indicator-free electrochemical DNA hybridization biosensor
journal, November 1998
- Wang, Joseph; Rivas, Gustavo; Fernandes, Joao Roberto
- Analytica Chimica Acta, Vol. 375, Issue 3
Biocatalytic precipitation induced by an affinity reaction on dendrimer-activated surfaces for the electrochemical signaling from immunosensors
journal, July 2002
- Yoon, Hyun C.; Yang, Haesik; Kim, Youn Tae
- The Analyst, Vol. 127, Issue 8
DNA hybridization at microbeads with cathodic stripping voltammetric detection
journal, April 2002
- Palecek, E.
- Talanta, Vol. 56, Issue 5